EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway

Sustaining a high growth rate requires tumors to exploit resources in their microenvironment. One example of this is the extensive angiogenesis that is a typical feature of high-grade gliomas. Here, we show that expression of the constitutively active mutant epidermal growth factor receptor, ΔEGFR (...

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Detalhes bibliográficos
Main Authors: Bonavia, R, Inda, MM, Vandenberg, S, Cheng, S-Y, Nagane, M, Hadwiger, P, Tan, P, Sah, DWY, Cavenee, WK, Furnari, FB
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537826/
https://ncbi.nlm.nih.gov/pubmed/22139077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.563
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