EGFRvIII uses intrinsic and extrinsic mechanisms to reduce glioma adhesion and increase migration

A lack of biological markers has limited our ability to identify the invasive cells responsible for glioblastoma multiforme (GBM). To become migratory and invasive, cells must downregulate matrix adhesions, which could be a physical marker of invasive potential. We engineered murine astrocytes with...

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Udgivet i:J Cell Sci
Main Authors: Banisadr, Afsheen, Eick, Mariam, Beri, Pranjali, Parisian, Alison D., Yeoman, Benjamin, Placone, Jesse K., Engler, Adam J., Furnari, Frank
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7774888/
https://ncbi.nlm.nih.gov/pubmed/33243756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.247189
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