Analysis of disease progression in patients with transthyretin cardiac amyloidosis

Por Gilmore, Julian D, Maurer, Mathew S, Vest, John, Karsten, Verena, Powell, Christine, Strahs, Andrew, Gollob, Jared, Hawkins, Philip N
Publicado no Orphanet J Rare Dis (2015)

A status report on RNAi therapeutics

Por Vaishnaw, Akshay K, Gollob, Jared, Gamba-Vitalo, Christina, Hutabarat, Renta, Sah, Dinah, Meyers, Rachel, de Fougerolles, Tony, Maraganore, John
Publicado em 2010

Phase 2, open-label extension (OLE) study of revusiran, an investigational RNAi therapeutic for the treatment of patients with transthyretin cardiac amyloidosis

Por Gillmore, Julian D, Falk, Rodney H, Maurer, Mathew S, Hanna, Mazen, Karsten, Verena, Vest, John, Gollob, Jared, Hawkins, Philip N
Publicado no Orphanet J Rare Dis (2015)

A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus

Por DeVincenzo, John, Lambkin-Williams, Robert, Wilkinson, Tom, Cehelsky, Jeffrey, Nochur, Sara, Walsh, Edward, Meyers, Rachel, Gollob, Jared, Vaishnaw, Akshay
Publicado em 2010

Trial design and rationale for APOLLO, a Phase 3, placebo-controlled study of patisiran in patients with hereditary ATTR amyloidosis with polyneuropathy

Por Adams, David, Suhr, Ole B., Dyck, Peter J., Litchy, William J., Leahy, Raina G., Chen, Jihong, Gollob, Jared, Coelho, Teresa
Publicado no BMC Neurol (2017)

Clinical Proof of Concept for a Novel Hepatocyte-Targeting GalNAc-siRNA Conjugate

Por Zimmermann, Tracy S., Karsten, Verena, Chan, Amy, Chiesa, Joseph, Boyce, Malcolm, Bettencourt, Brian R., Hutabarat, Renta, Nochur, Saraswathy, Vaishnaw, Akshay, Gollob, Jared
Publicado no Mol Ther (2017)

Rapid progression of familial amyloidotic polyneuropathy: A multinational natural history study

Por Adams, David, Coelho, Teresa, Obici, Laura, Merlini, Giampaolo, Mincheva, Zoia, Suanprasert, Narupat, Bettencourt, Brian R., Gollob, Jared A., Gandhi, Pritesh J., Litchy, William J., Dyck, Peter J.
Publicado no Neurology (2015)

Serial scanning with technetium pyrophosphate ((99m)Tc-PYP) in advanced ATTR cardiac amyloidosis

Por Castaño, Adam, DeLuca, Albert, Weinberg, Richard, Pozniakoff, Ted, Blaner, William S., Pirmohamed, Altaf, Bettencourt, Brian, Gollob, Jared, Karsten, Verena, Vest, John A., Chiuzan, Codruta, Maurer, Mathew S., Bokhari, Sabahat
Publicado no J Nucl Cardiol (2015)

Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study

Por Suhr, Ole B, Coelho, Teresa, Buades, Juan, Pouget, Jean, Conceicao, Isabel, Berk, John, Schmidt, Hartmut, Waddington-Cruz, Márcia, Campistol, Josep M., Bettencourt, Brian R., Vaishnaw, Akshay, Gollob, Jared, Adams, David
Publicado no Orphanet J Rare Dis (2015)

Evaluation of Therapeutic Oligonucleotides for Familial Amyloid Polyneuropathy in Patient-Derived Hepatocyte-Like Cells

Por Niemietz, Christoph J., Sauer, Vanessa, Stella, Jacqueline, Fleischhauer, Lutz, Chandhok, Gursimran, Guttmann, Sarah, Avsar, Yesim, Guo, Shuling, Ackermann, Elizabeth J., Gollob, Jared, Monia, Brett P., Zibert, Andree, Schmidt, Hartmut H. -J.
Publicado no PLoS One (2016)

Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a...

Por Fitzgerald, Kevin, Frank-Kamenetsky, Maria, Shulga-Morskaya, Svetlana, Liebow, Abigail, Bettencourt, Brian R, Sutherland, Jessica E, Hutabarat, Renta M, Clausen, Valerie A, Karsten, Verena, Cehelsky, Jeffrey, Nochur, Saraswathy V, Kotelianski, Victor, Horton, Jay, Mant, Timothy, Chiesa, Joseph, Ritter, James, Munisamy, Malathy, Vaishnaw, Akshay K, Gollob, Jared A, Simon, Amy
Publicado no Lancet (2013)

Defining the critical hurdles in cancer immunotherapy

Por Fox, Bernard A, Schendel, Dolores J, Butterfield, Lisa H, Aamdal, Steinar, Allison, James P, Ascierto, Paolo Antonio, Atkins, Michael B, Bartunkova, Jirina, Bergmann, Lothar, Berinstein, Neil, Bonorino, Cristina C, Borden, Ernest, Bramson, Jonathan L, Britten, Cedrik M, Cao, Xuetao, Carson, William E, Chang, Alfred E, Characiejus, Dainius, Choudhury, A Raja, Coukos, George, de Gruijl, Tanja, Dillman, Robert O, Dolstra, Harry, Dranoff, Glenn, Durrant, Lindy G, Finke, James H, Galon, Jerome, Gollob, Jared A, Gouttefangeas, Cécile, Grizzi, Fabio, Guida, Michele, Håkansson, Leif, Hege, Kristen, Herberman, Ronald B, Hodi, F Stephen, Hoos, Axel, Huber, Christoph, Hwu, Patrick, Imai, Kohzoh, Jaffee, Elizabeth M, Janetzki, Sylvia, June, Carl H, Kalinski, Pawel, Kaufman, Howard L, Kawakami, Koji, Kawakami, Yutaka, Keilholtz, Ulrich, Khleif, Samir N, Kiessling, Rolf, Kotlan, Beatrix, Kroemer, Guido, Lapointe, Rejean, Levitsky, Hyam I, Lotze, Michael T, Maccalli, Cristina, Maio, Michele, Marschner, Jens-Peter, Mastrangelo, Michael J, Masucci, Giuseppe, Melero, Ignacio, Melief, Cornelius, Murphy, William J, Nelson, Brad, Nicolini, Andrea, Nishimura, Michael I, Odunsi, Kunle, Ohashi, Pamela S, O'Donnell-Tormey, Jill, Old, Lloyd J, Ottensmeier, Christian, Papamichail, Michael, Parmiani, Giorgio, Pawelec, Graham, Proietti, Enrico, Qin, Shukui, Rees, Robert, Ribas, Antoni, Ridolfi, Ruggero, Ritter, Gerd, Rivoltini, Licia, Romero, Pedro J, Salem, Mohamed L, Scheper, Rik J, Seliger, Barbara, Sharma, Padmanee, Shiku, Hiroshi, Singh-Jasuja, Harpreet, Song, Wenru, Straten, Per Thor, Tahara, Hideaki, Tian, Zhigang, van Der Burg, Sjoerd H, von Hoegen, Paul, Wang, Ena, Welters, Marij JP, Winter, Hauke, Withington, Tara, Wolchok, Jedd D, Xiao, Weihua, Zitvogel, Laurence, Zwierzina, Heinz, Marincola, Francesco M, Gajewski, Thomas F, Wigginton, Jon M, Disis, Mary L
Publicado em 2011