Impact of voxelotor (GBT440) on unconjugated bilirubin and jaundice in sickle cell disease

Por Telfer, Paul, Agodoa, Irene, Fox, Kathleen M., Burke, Laurie, Mant, Timothy, Jurek, Marzena, Tonda, Margaret, Lehrer-Graiwer, Josh
Publicado no Hematol Rep (2018)

Pharmacokinetics and safety assessments of high-dose and 4-week treatment with S-3304, a novel matrix metalloproteinase inhibitor, in healthy volunteers

Por Mant, Timothy G K, Bradford, Daniel, Amin, Dipti M, Pisupati, Jaya, Kambayashi, Yoshikazu, Yano, Yoshitaka, Tanaka, Kazushige, Yamada-Sawada, Takuko
Publicado em 2007

An S‐warfarin and AZD1981 interaction: in vitro and clinical pilot data suggest the N‐deacetylated amino acid metabolite as the primary perpetrator

Por Grime, Ken, Pehrson, Rikard, Nordell, Pär, Gillen, Michael, Kühn, Wolfgang, Mant, Timothy, Brännström, Marie, Svanberg, Petter, Jones, Barry, Brealey, Clive
Publicado no Br J Clin Pharmacol (2016)

Safety and patient response as indicated by biomarker changes to binding immunoglobulin protein in the phase I/IIA RAGULA clinical trial in rheumatoid arthritis

Por Kirkham, Bruce, Chaabo, Khaldoun, Hall, Christopher, Garrood, Toby, Mant, Timothy, Allen, Elizabeth, Vincent, Alexandra, Vasconcelos, Joana C., Prevost, Andrew T., Panayi, Gabriel S., Corrigall, Valerie M.
Publicado no Rheumatology (Oxford) (2016)

A phase 1 study of prasugrel in patients with sickle cell disease: pharmacokinetics and effects on ex vivo platelet reactivity

Por Jakubowski, Joseph A, Zhou, Chunmei, Small, David S, Winters, Kenneth J, Lachno, D Richard, Frelinger, Andrew L, Howard, Jo, Mant, Timothy G, Jurcevic, Stipo, Payne, Christopher D
Publicado em 2013

Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a...

Por Fitzgerald, Kevin, Frank-Kamenetsky, Maria, Shulga-Morskaya, Svetlana, Liebow, Abigail, Bettencourt, Brian R, Sutherland, Jessica E, Hutabarat, Renta M, Clausen, Valerie A, Karsten, Verena, Cehelsky, Jeffrey, Nochur, Saraswathy V, Kotelianski, Victor, Horton, Jay, Mant, Timothy, Chiesa, Joseph, Ritter, James, Munisamy, Malathy, Vaishnaw, Akshay K, Gollob, Jared A, Simon, Amy
Publicado no Lancet (2013)