GBT440 Inhibits Sickling of Sickle Cell Trait Blood Under In Vitro Conditions Mimicking Strenuous Exercise

Por Dufu, Kobina, Lehrer-Graiwer, Josh, Ramos, Eleanor, Oksenberg, Donna
Publicado no Hematol Rep (2016)

Impact of voxelotor (GBT440) on unconjugated bilirubin and jaundice in sickle cell disease

Por Telfer, Paul, Agodoa, Irene, Fox, Kathleen M., Burke, Laurie, Mant, Timothy, Jurek, Marzena, Tonda, Margaret, Lehrer-Graiwer, Josh
Publicado no Hematol Rep (2018)

Increased hemoglobin–oxygen affinity ameliorates bleomycin‐induced hypoxemia and pulmonary fibrosis

Por Geng, Xin, Dufu, Kobina, Hutchaleelaha, Athiwat, Xu, Qing, Li, Zhe, Li, Chien‐Ming, Patel, Mira P., Vlahakis, Nicholas, Lehrer‐Graiwer, Josh, Oksenberg, Donna
Publicado no Physiol Rep (2016)

GBT1118, a potent allosteric modifier of hemoglobin O(2) affinity, increases tolerance to severe hypoxia in mice

Por Dufu, Kobina, Yalcin, Ozlem, Ao-ieong, Eilleen S. Y., Hutchaleelala, Athiwat, Xu, Qing, Li, Zhe, Vlahakis, Nicholas, Oksenberg, Donna, Lehrer-Graiwer, Josh, Cabrales, Pedro
Publicado no Am J Physiol Heart Circ Physiol (2017)