Improved MHC II epitope prediction — a step towards personalized medicine

Por Moore, Tamson V., Nishimura, Michael I.
Publicado no Nat Rev Clin Oncol (2019)

Strategies to genetically engineer T cells for cancer immunotherapy

Por Spear, Timothy T., Nagato, Kaoru, Nishimura, Michael I.
Publicado no Cancer Immunol Immunother (2016)

Retroviral transduction of peptide stimulated t cells can generate dual t cell receptor-expressing (bifunctional) t cells reactive with two defined antigens

Por Langerman, Alexander, Callender, Glenda G, Nishimura, Michael I
Publicado em 2004

Comparative exploration of multidimensional flow cytometry software: a model approach evaluating T cell polyfunctional behavior

Por Spear, Timothy T., Nishimura, Michael I., Simms, Patricia E.
Publicado no J Leukoc Biol (2017)

Adoptive immunotherapy of cancer: Gene transfer of T cell specificity

Por Al-Khami, Amir A, Mehrotra, Shikhar, Nishimura, Michael I
Publicado em 2011

Combination Immunotherapies Implementing Adoptive T Cell Transfer for Advanced-Stage Melanoma

Por Foley, Kendra C., Nishimura, Michael I., Moore, Tamson V.
Publicado no Melanoma Res (2018)

Activated human Foxp3(+) regulatory T cells produce membrane-bound TNF

Por Nelson, Alexander, Cunha, Christina, Nishimura, Michael I., Iwashima, Makio
Publicado no Cytokine (2018)

T cell avidity and tumor recognition: implications and therapeutic strategies

Por McKee, Mark D, Roszkowski, Jeffrey J, Nishimura, Michael I
Publicado em 2005

TCR modifications that enhance chain pairing in gene-modified T cells can augment cross-reactivity and alleviate CD8-dependence

Por Spear, Timothy T., Foley, Kendra C., Garrett-Mayer, Elizabeth, Nishimura, Michael I.
Publicado no J Leukoc Biol (2018)

Characterization of MHC class-I restricted TCRαβ(+) CD4(−) CD8(−) double negative T cells recognizing the gp100 antigen from a melanoma patient after gp100 vaccination

Por Voelkl, Simon, Moore, Tamson V., Rehli, Michael, Nishimura, Michael I., Mackensen, Andreas, Fischer, Karin
Publicado em 2008

Inducible Enhancement of T Cell Function and Anti-tumor Activity after Adoptive Transfer

Por Wrangle, John, Paulos, Chrystal M., Smith, Thomas W., Nishimura, Michael I., Rubinstein, Mark P.
Publicado no Mol Ther (2017)

HCV T Cell Receptor Chain Modifications to Enhance Expression, Pairing, and Antigen Recognition in T Cells for Adoptive Transfer

Por Foley, Kendra C., Spear, Timothy T., Murray, David C., Nagato, Kaoru, Garrett-Mayer, Elizabeth, Nishimura, Michael I.
Publicado no Mol Ther Oncolytics (2017)

Efficacy of adoptive T cell therapy is improved by treatment with the antioxidant N-acetyl cysteine, which limits activation-induced T cell death

Por Scheffel, Matthew J., Scurti, Gina, Simms, Patricia, Garrett-Mayer, Elizabeth, Mehrotra, Shikhar, Nishimura, Michael I., Voelkel-Johnson, Christina
Publicado no Cancer Res (2016)

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy

Por Diaz-Montero, C. Marcela, Salem, Mohamed Labib, Nishimura, Michael I., Garrett-Mayer, Elizabeth, Cole, David J., Montero, Alberto J.
Publicado em 2008

Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanisms

Por Muller, Laurent, Simms, Patricia, Hong, Chang-Sook, Nishimura, Michael I., Jackson, Edwin K., Watkins, Simon C., Whiteside, Theresa L.
Publicado no Oncoimmunology (2017)

N-acetyl cysteine protects anti-melanoma cytotoxic T cells from exhaustion induced by rapid expansion via the downmodulation of Foxo1 in an Akt-dependent manner

Por Scheffel, Matthew J., Scurti, Gina, Wyatt, Megan M., Garrett-Mayer, Elizabeth, Paulos, Chrystal M., Nishimura, Michael I., Voelkel-Johnson, Christina
Publicado no Cancer Immunol Immunother (2018)

Cloning and Characterization of the Genes Encoding the Murine Homologues of the Human Melanoma Antigens MART1 and gp100

Por Zhai, Yifan, Yang, James C., Spiess, Paul, Nishimura, Michael I., Overwijk, Willem W., Roberts, Bruce, Restifo, Nicholas P., Rosenberg, Steven A.
Publicado em 1997

Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses

Por Koya, Richard C., Mok, Stephen, Comin-Anduix, Begoña, Chodon, Thinle, Radu, Caius G., Nishimura, Michael I., Witte, Owen N., Ribas, Antoni
Publicado em 2010

Altered Peptide Ligands Impact the Diversity of Polyfunctional Phenotypes in T Cell Receptor Gene-Modified T Cells

Por Spear, Timothy T., Wang, Yuan, Smith, Thomas W., Simms, Patricia E., Garrett-Mayer, Elizabeth, Hellman, Lance M., Baker, Brian M., Nishimura, Michael I.
Publicado no Mol Ther (2018)

T-Cell Recognition of Human Melanoma Antigens

Por Kawakami, Yutaka, Nishimura, Michael I., Restifo, Nicholas P., Topalian, Suzanne L., O’Neil, Bert H., Shilyansky, Joel, Yannelli, John R., Rosenberg, Steven A.
Publicado em 1993