Human tumor-derived exosomes (TEX) regulate Treg functions via cell surface signaling rather than uptake mechanisms

Tumor-derived exosomes (TEX) are ubiquitously present in the tumor microenvironment and plasma of cancer patients. TEX carry a cargo of multiple stimulatory and inhibitory molecules and deliver them to recipient cells, serving as a communication network for the tumor. The mechanisms TEX use for deli...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Muller, Laurent, Simms, Patricia, Hong, Chang-Sook, Nishimura, Michael I., Jackson, Edwin K., Watkins, Simon C., Whiteside, Theresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593709/
https://ncbi.nlm.nih.gov/pubmed/28919985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1261243
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