Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses

A key issue in advancing the use of adoptive cell transfer (ACT) of T cell receptor (TCR) engineered lymphocytes for cancer therapy is demonstrating how TCR transgenic cells repopulate lymphopenic hosts and target tumors in an antigen-specific fashion. ACT of splenocytes from fully immunocompetent H...

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Hlavní autoři: Koya, Richard C., Mok, Stephen, Comin-Anduix, Begoña, Chodon, Thinle, Radu, Caius G., Nishimura, Michael I., Witte, Owen N., Ribas, Antoni
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922609/
https://ncbi.nlm.nih.gov/pubmed/20624956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1008300107
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