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Characterization of MHC class-I restricted TCRαβ(+) CD4(−) CD8(−) double negative T cells recognizing the gp100 antigen from a melanoma patient after gp100 vaccination
The immune attack against malignant tumors requires the concerted action of CD8(+) cytotoxic T lymphocytes (CTL) as well as CD4(+) T helper cells. The contribution of T cell receptor (TCR)αβ(+) CD4(−) CD8(−) double-negative (DN) T cells to anti-tumor immune responses is widely unknown. In previous s...
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Autori principali: | , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2008
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2832593/ https://ncbi.nlm.nih.gov/pubmed/18836718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-008-0593-3 |
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