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Induction of CD4(+) Th1 Lymphocytes That Recognize Known and Novel Class II MHC Restricted Epitopes from the Melanoma Antigen gp100 by Stimulation with Recombinant Protein

CD4(+) T helper cells may play a critical role in the induction and maintenance of a therapeutic immune response to cancer. To evaluate the efficacy with which a recombinant tumor-associated protein can induce antigen-reactive CD4(+) T cells, we stimulated peripheral blood lymphocytes from patients...

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Auteurs principaux: Parkhurst, Maria R., Riley, John P., Robbins, Paul F., Rosenberg, Steven A.
Format: Artigo
Langue:Inglês
Publié: 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275328/
https://ncbi.nlm.nih.gov/pubmed/14770079
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