A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus

RNA interference (RNAi) is a natural mechanism regulating protein expression that is mediated by small interfering RNAs (siRNA). Harnessing RNAi has potential to treat human disease; however, clinical evidence for the effectiveness of this therapeutic approach is lacking. ALN-RSV01 is an siRNA direc...

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Autori principali: DeVincenzo, John, Lambkin-Williams, Robert, Wilkinson, Tom, Cehelsky, Jeffrey, Nochur, Sara, Walsh, Edward, Meyers, Rachel, Gollob, Jared, Vaishnaw, Akshay
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889365/
https://ncbi.nlm.nih.gov/pubmed/20421463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912186107
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