Eukaryotic Translation Initiation Factors 4G and 4A from Saccharomyces cerevisiae Interact Physically and Functionally

door Neff, Carrie L., Sachs, Alan B.
Gepubliceerd in 1999

Poly(A) Tail Length Control in Saccharomyces cerevisiae Occurs by Message-Specific Deadenylation

door Brown, Christine E., Sachs, Alan B.
Gepubliceerd in 1998

RNA Recognition Motif 2 of Yeast Pab1p Is Required for Its Functional Interaction with Eukaryotic Translation Initiation Factor 4G

door Kessler, Steven H., Sachs, Alan B.
Gepubliceerd in 1998

Glucose Depletion Rapidly Inhibits Translation Initiation in Yeast

door Ashe, Mark P., De Long, Susan K., Sachs, Alan B.
Gepubliceerd in 2000

Capped mRNA Degradation Intermediates Accumulate in the Yeast spb8-2 Mutant

door Boeck, Ronald, Lapeyre, Bruno, Brown, Christine E., Sachs, Alan B.
Gepubliceerd in 1998

Translation initiation factor eIF4G mediates in vitro poly(A) tail-dependent translation

door Tarun, Salvador Z., Wells, Sandra E., Deardorff, Julie A., Sachs, Alan B.
Gepubliceerd in 1997

Persistence of seed-based activity following segmentation of a microRNA guide strand

door Chorn, Guillaume, Zhao, Lihong, Sachs, Alan B., Flanagan, W. Michael, Lim, Lee P.
Gepubliceerd in 2010

A novel eIF2B-dependent mechanism of translational control in yeast as a response to fusel alcohols

door Ashe, Mark P., Slaven, John W., De Long, Susan K., Ibrahimo, Sálma, Sachs, Alan B.
Gepubliceerd in 2001

One-step affinity purification of the yeast ribosome and its associated proteins and mRNAs.

door Inada, Toshifumi, Winstall, Eric, Tarun, Salvador Z, Yates, John R, Schieltz, Dave, Sachs, Alan B
Gepubliceerd in 2002

Mechanistically Probing Lipid-siRNA Nanoparticle-associated Toxicities Identifies Jak Inhibitors Effective in Mitigating Multifaceted Toxic Responses

door Tao, Weikang, Mao, Xianzhi, Davide, Joseph P, Ng, Bruce, Cai, Mingmei, Burke, Paul A, Sachs, Alan B, Sepp-Lorenzino, Laura
Gepubliceerd in 2011

MicroRNA-like off-target transcript regulation by siRNAs is species specific

door Burchard, Julja, Jackson, Aimee L., Malkov, Vladislav, Needham, Rachel H.V., Tan, Yejun, Bartz, Steven R., Dai, Hongyue, Sachs, Alan B., Linsley, Peter S.
Gepubliceerd in 2009

Biodistribution of Small Interfering RNA at the Organ and Cellular Levels after Lipid Nanoparticle-mediated Delivery

door Shi, Bin, Keough, Ed, Matter, Andrea, Leander, Karen, Young, Stephanie, Carlini, Ed, Sachs, Alan B., Tao, Weikang, Abrams, Marc, Howell, Bonnie, Sepp-Lorenzino, Laura
Gepubliceerd in 2011

ApoB siRNA-induced Liver Steatosis is Resistant to Clearance by the Loss of Fatty Acid Transport Protein 5 (Fatp5)

door Ason, Brandon, Castro-Perez, Jose, Tep, Samnang, Stefanni, Alice, Tadin-Strapps, Marija, Roddy, Thomas, Hankemeier, Thomas, Hubbard, Brian, Sachs, Alan B., Michael Flanagan, W., Kuklin, Nelly A., Mitnaul, Lyndon J.
Gepubliceerd in 2011

Development and characterization of a reconstituted yeast translation initiation system.

door Algire, Mikkel A, Maag, David, Savio, Peter, Acker, Michael G, Tarun, Salvador Z, Sachs, Alan B, Asano, Katsura, Nielsen, Klaus H, Olsen, Deanne S, Phan, Lon, Hinnebusch, Alan G, Lorsch, Jon R
Gepubliceerd in 2002

Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5′-terminal phosphorylation both in vitro and in vivo

door Kenski, Denise M., Cooper, Abby J., Li, Jenny J., Willingham, Aarron T., Haringsma, Henry J., Young, Tracy A., Kuklin, Nelly A., Jones, Jeffrey J., Cancilla, Mark T., McMasters, Daniel R., Mathur, Melina, Sachs, Alan B., Flanagan, W. Michael
Gepubliceerd in 2010

Evaluation of Efficacy, Biodistribution, and Inflammation for a Potent siRNA Nanoparticle: Effect of Dexamethasone Co-treatment

door Abrams, Marc T, Koser, Martin L, Seitzer, Jessica, Williams, Stephanie C, DiPietro, Martha A, Wang, Weimin, Shaw, Andrew W, Mao, Xianzhi, Jadhav, Vasant, Davide, Joseph P, Burke, Paul A, Sachs, Alan B, Stirdivant, Steven M, Sepp-Lorenzino, Laura
Gepubliceerd in 2009

Quantitative evaluation of siRNA delivery in vivo

door Pei, Yi, Hancock, Paula J., Zhang, Hangchun, Bartz, René, Cherrin, Craig, Innocent, Nathalie, Pomerantz, Colin J., Seitzer, Jessica, Koser, Martin L., Abrams, Marc T., Xu, Yan, Kuklin, Nelly A., Burke, Paul A., Sachs, Alan B., Sepp-Lorenzino, Laura, Barnett, Stanley F.
Gepubliceerd in 2010

Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9

door Ason, Brandon, Tep, Samnang, Davis, Harry R., Xu, Yiming, Tetzloff, Glen, Galinski, Beverly, Soriano, Ferdie, Dubinina, Natalya, Zhu, Lei, Stefanni, Alice, Wong, Kenny K., Tadin-Strapps, Marija, Bartz, Steven R., Hubbard, Brian, Ranalletta, Mollie, Sachs, Alan B., Flanagan, W. Michael, Strack, Alison, Kuklin, Nelly A.
Gepubliceerd in 2011

LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease

door Majercak, John, Ray, William J., Espeseth, Amy, Simon, Adam, Shi, Xiao-Ping, Wolffe, Carrie, Getty, Krista, Marine, Shane, Stec, Erica, Ferrer, Marc, Strulovici, Berta, Bartz, Steven, Gates, Adam, Xu, Min, Huang, Qian, Ma, Lei, Shughrue, Paul, Burchard, Julja, Colussi, Dennis, Pietrak, Beth, Kahana, Jason, Beher, Dirk, Rosahl, Thomas, Shearman, Mark, Hazuda, Daria, Sachs, Alan B., Koblan, Kenneth S., Seabrook, Guy R., Stone, David J.
Gepubliceerd in 2006

siRNA-induced liver ApoB knockdown lowers serum LDL-cholesterol in a mouse model with human-like serum lipids

door Tadin-Strapps, Marija, Peterson, Laurence B., Cumiskey, Anne-Marie, Rosa, Raymond L., Mendoza, Vivienne Halili, Castro-Perez, Jose, Puig, Oscar, Zhang, Liwen, Strapps, Walter R., Yendluri, Satyasri, Andrews, Lori, Pickering, Victoria, Rice, Julie, Luo, Lily, Chen, Zhu, Tep, Samnang, Ason, Brandon, Somers, Elizabeth Polizzi, Sachs, Alan B., Bartz, Steven R., Tian, Jenny, Chin, Jayne, Hubbard, Brian K., Wong, Kenny K., Mitnaul, Lyndon J.
Gepubliceerd in 2011