Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms

Autor Ross, Fiona A., Jensen, Thomas E., Hardie, D. Grahame
Vydáno v Biochem J (2016)

AMP‐activated protein kinase: a cellular energy sensor that comes in 12 flavours

Autor Ross, Fiona A., MacKintosh, Carol, Hardie, D. Grahame
Vydáno v FEBS J (2016)

AMP-activated protein kinase: a target for drugs both ancient and modern

Autor Hardie, D. Grahame, Ross, Fiona A., Hawley, Simon A.
Vydáno v Chem Biol (2012)

AMPK - a nutrient and energy sensor that maintains energy homeostasis

Autor Hardie, D. Grahame, Ross, Fiona A., Hawley, Simon A.
Vydáno v Nat Rev Mol Cell Biol (2012)

Oxidative stress activates AMPK in cultured cells primarily by increasing cellular AMP and/or ADP

Autor Auciello, F. Romana, Ross, Fiona A., Ikematsu, Naoko, Hardie, D. Grahame
Vydáno 2014

AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation

Autor Gowans, Graeme J., Hawley, Simon A., Ross, Fiona A., Hardie, D. Grahame
Vydáno 2013

Regulation of AMP-activated protein kinase by a pseudosubstrate sequence on the γ subunit

Autor Scott, John W, Ross, Fiona A, Liu, J K David, Hardie, D Grahame
Vydáno 2007

AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2

Autor Fogarty, Sarah, Ross, Fiona A., Ciruelos, Diana Vara, Gray, Alexander, Gowans, Graeme J., Hardie, D. Grahame
Vydáno v Mol Cancer Res (2016)

Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells

Autor Hawley, Simon A., Ross, Fiona A., Gowans, Graeme J., Tibarewal, Priyanka, Leslie, Nicholas R., Hardie, D. Grahame
Vydáno 2014

Mechanism of Activation of AMPK by Cordycepin

Autor Hawley, Simon A., Ross, Fiona A., Russell, Fiona M., Atrih, Abdelmadjid, Lamont, Douglas J., Hardie, D. Grahame
Vydáno v Cell Chem Biol (2020)

AMP‐activated protein kinase inhibits K(v)1.5 channel currents of pulmonary arterial myocytes in response to hypoxia and inhibition of mitochondrial oxidative phosphorylation

Autor Moral‐Sanz, Javier, Mahmoud, Amira D., Ross, Fiona A., Eldstrom, Jodene, Fedida, David, Hardie, D. Grahame, Evans, A. Mark
Vydáno v J Physiol (2016)

PT-1 selectively activates AMPK-γ1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain

Autor Jensen, Thomas E., Ross, Fiona A., Kleinert, Maximilian, Sylow, Lykke, Knudsen, Jonas R., Hardie, D. Grahame, Richter, Erik A.
Vydáno v Biochem J (2015)

Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib

Autor Ross, Fiona A., Hawley, Simon A., Auciello, F. Romana, Gowans, Graeme J., Atrih, Abdelmadjid, Lamont, Douglas J., Hardie, D. Grahame
Vydáno v Cell Chem Biol (2017)

MECHANISM OF ACTION OF A-769662, A VALUABLE TOOL FOR ACTIVATION OF AMP-ACTIVATED PROTEIN KINASE

Autor Göransson, Olga, McBride, Andrew, Hawley, Simon A., Ross, Fiona A., Shpiro, Natalia, Foretz, Marc, Viollet, Benoit, Hardie, D. Grahame, Sakamoto, Kei
Vydáno 2007

Bitter Melon (Momordica charantia) Extract Inhibits Tumorigenicity and Overcomes Cisplatin-Resistance in Ovarian Cancer Cells Through Targeting AMPK Signaling Cascade

Autor Yung, Mingo M. H., Ross, Fiona A., Hardie, D. Grahame, Leung, Thomas H. Y., Zhan, Jinbiao, Ngan, Hextan Y. S., Chan, David W.
Vydáno v Integr Cancer Ther (2015)

Phosphorylation of the voltage-gated potassium channel Kv2.1 by AMP-activated protein kinase regulates membrane excitability

Autor Ikematsu, Naoko, Dallas, Mark L., Ross, Fiona A., Lewis, Ryan W., Rafferty, J. Nicole, David, Jonathan A., Suman, Rakesh, Peers, Chris, Hardie, D. Grahame, Evans, A. Mark
Vydáno 2011

Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation

Autor Hawley, Simon A., Ross, Fiona A., Chevtzoff, Cyrille, Green, Kevin A., Evans, Ashleigh, Fogarty, Sarah, Towler, Mhairi C., Brown, Laura J., Ogunbayo, Oluseye A., Evans, A. Mark, Hardie, D. Grahame
Vydáno 2010

Mechanism of Action of Compound-13: An α1-Selective Small Molecule Activator of AMPK

Autor Hunter, Roger W., Foretz, Marc, Bultot, Laurent, Fullerton, Morgan D., Deak, Maria, Ross, Fiona A., Hawley, Simon A., Shpiro, Natalia, Viollet, Benoit, Barron, Denis, Kemp, Bruce E., Steinberg, Gregory R., Hardie, D. Grahame, Sakamoto, Kei
Vydáno 2014

Selective Expression in Carotid Body Type I Cells of a Single Splice Variant of the Large Conductance Calcium- and Voltage-activated Potassium Channel Confers Regulation by AMP-act...

Autor Ross, Fiona A., Rafferty, J. Nicole, Dallas, Mark L., Ogunbayo, Oluseye, Ikematsu, Naoko, McClafferty, Heather, Tian, Lijun, Widmer, Helene, Rowe, Iain C. M., Wyatt, Christopher N., Shipston, Michael J., Peers, Chris, Hardie, D. Grahame, Evans, A. Mark
Vydáno 2011

The ancient drug salicylate directly activates AMP-activated protein kinase

Autor Hawley, Simon A., Fullerton, Morgan D., Ross, Fiona A., Schertzer, Jonathan D., Chevtzoff, Cyrille, Walker, Katherine J., Peggie, Mark W., Zibrova, Darya, Green, Kevin A., Mustard, Kirsty J., Kemp, Bruce E., Sakamoto, Kei, Steinberg, Gregory R., Hardie, D. Grahame
Vydáno 2012