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Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells
The insulin/IGF-1 (insulin-like growth factor 1)-activated protein kinase Akt (also known as protein kinase B) phosphorylates Ser(487) in the ‘ST loop’ (serine/threonine-rich loop) within the C-terminal domain of AMPK-α1 (AMP-activated protein kinase-α1), leading to inhibition of phosphorylation by...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Portland Press Ltd.
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4052680/ https://ncbi.nlm.nih.gov/pubmed/24467442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131344 |
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