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Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms

The γ subunits of heterotrimeric AMPK complexes contain the binding sites for the regulatory adenine nucleotides AMP, ADP and ATP. We addressed whether complexes containing different γ isoforms display different responses to adenine nucleotides by generating cells stably expressing FLAG-tagged versi...

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Bibliographic Details
Published in:Biochem J
Main Authors: Ross, Fiona A., Jensen, Thomas E., Hardie, D. Grahame
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700476/
https://ncbi.nlm.nih.gov/pubmed/26542978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20150910
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