Selective Expression in Carotid Body Type I Cells of a Single Splice Variant of the Large Conductance Calcium- and Voltage-activated Potassium Channel Confers Regulation by AMP-activated Protein Kinase

Inhibition of large conductance calcium-activated potassium (BK(Ca)) channels mediates, in part, oxygen sensing by carotid body type I cells. However, BK(Ca) channels remain active in cells that do not serve to monitor oxygen supply. Using a novel, bacterially derived AMP-activated protein kinase (A...

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Main Authors: Ross, Fiona A., Rafferty, J. Nicole, Dallas, Mark L., Ogunbayo, Oluseye, Ikematsu, Naoko, McClafferty, Heather, Tian, Lijun, Widmer, Helene, Rowe, Iain C. M., Wyatt, Christopher N., Shipston, Michael J., Peers, Chris, Hardie, D. Grahame, Evans, A. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069395/
https://ncbi.nlm.nih.gov/pubmed/21209098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.189779
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