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An Electrostatic Switch Controls Palmitoylation of the Large Conductance Voltage- and Calcium-activated Potassium (BK) Channel

Protein palmitoylation is a major dynamic posttranslational regulator of protein function. However, mechanisms that control palmitoylation are poorly understood. In many proteins, palmitoylation occurs at cysteine residues juxtaposed to membrane-anchoring domains such as transmembrane helices, sites...

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Detalhes bibliográficos
Main Authors: Jeffries, Owen, Tian, Lijun, McClafferty, Heather, Shipston, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256903/
https://ncbi.nlm.nih.gov/pubmed/22084244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.224840
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