A subunit of coatomer protein complex offers a novel tumor-specific target through a surprising mechanism

Tekijä Shtutman, Michael, Roninson, Igor B.
Julkaistu 2011

Regulation of Sp1 by cell cycle related proteins

Tekijä Tapias, Alicia, Ciudad, Carlos J., Roninson, Igor B., Noé, Véronique
Julkaistu 2008

Role of transcription-regulating kinase CDK8 in colon cancer metastasis

Tekijä Liang, Jiaxin, Chen, Mengqian, Broude, Eugenia V., Roninson, Igor B.
Julkaisussa Oncotarget (2019)

Repression of the SUMO-specific protease Senp1 induces p53-dependent premature senescence in normal human fibroblasts

Tekijä Yates, Kristin E., Korbel, Gregory A., Shtutman, Michael, Roninson, Igor B., DiMaio, Daniel
Julkaistu 2008

Effect of target secondary structure on RNAi efficiency

Tekijä Shao, Yu, Chan, Chi Yu, Maliyekkel, Anil, Lawrence, Charles E., Roninson, Igor B., Ding, Ye
Julkaistu 2007

Characterizing CDK8/19 Inhibitors through a NFκB-Dependent Cell-Based Assay

Tekijä Li, Jing, Ji, Hao, Porter, Donald C., Broude, Eugenia V., Roninson, Igor B., Chen, Mengqian
Julkaisussa Cells (2019)

Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent

Tekijä Chang, Bey-Dih, Swift, Mari E., Shen, Mei, Fang, Jing, Broude, Eugenia V., Roninson, Igor B.
Julkaistu 2002

Systemic Toxicity Reported for CDK8/19 Inhibitors CCT251921 and MSC2530818 Is Not Due to Target Inhibition

Tekijä Chen, Mengqian, Li, Jing, Liang, Jiaxin, Thompson, Zanshé S., Kathrein, Katie, Broude, Eugenia V., Roninson, Igor B.
Julkaisussa Cells (2019)

Identifying Cancers Impacted by CDK8/19

Tekijä Roninson, Igor B., Győrffy, Balázs, Mack, Zachary T., Shtil, Alexander A., Shtutman, Michael S., Chen, Mengqian, Broude, Eugenia V.
Julkaisussa Cells (2019)

A structural interpretation of the effect of GC-content on efficiency of RNA interference

Tekijä Chan, Chi Yu, Carmack, C Steven, Long, Dang D, Maliyekkel, Anil, Shao, Yu, Roninson, Igor B, Ding, Ye
Julkaistu 2009

Identification of single nucleotide polymorphisms in the p21 (CDKN1A) gene and correlations with longevity in the Italian population

Tekijä Gravina, Silvia, Lescai, Francesco, Hurteau, Gregory, Brock, Graham J., Saramaki, Anna, Salvioli, Stefano, Franceschi, Claudio, Roninson, Igor B.
Julkaistu 2009

Effects of p21(Waf1/Cip1/Sdi1) on cellular gene expression: Implications for carcinogenesis, senescence, and age-related diseases

Tekijä Chang, Bey-Dih, Watanabe, Keiko, Broude, Eugenia V., Fang, Jing, Poole, Jason C., Kalinichenko, Tatiana V., Roninson, Igor B.
Julkaistu 2000

P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity

Tekijä Mechetner, Eugene B., Schott, Brigitte, Morse, Brian S., Stein, Wilfred D., Druley, Todd, Davis, Kenneth A., Tsuruo, Takashi, Roninson, Igor B.
Julkaistu 1997

Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast Cancer

Tekijä Broude, Eugenia V., Győrffy, Balázs, Chumanevich, Alexander A., Chen, Mengqian, McDermott, Martina S. J., Shtutman, Michael, Catroppo, James F., Roninson, Igor B.
Julkaisussa Curr Cancer Drug Targets (2015)

Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1

Tekijä Alam, Amer, Küng, Raphael, Kowal, Julia, McLeod, Robert A., Tremp, Nina, Broude, Eugenia V., Roninson, Igor B., Stahlberg, Henning, Locher, Kaspar P.
Julkaisussa Proc Natl Acad Sci U S A (2018)

Function-based gene identification using enzymatically generated normalized shRNA library and massive parallel sequencing

Tekijä Shtutman, Michael, Maliyekkel, Anil, Shao, Yu, Carmack, C. Steven, Baig, Mirza, Warholic, Natalie, Cole, Kelly, Broude, Eugenia V., Harkins, Timothy T., Ding, Ye, Roninson, Igor B.
Julkaistu 2010

Reactive Oxygen Species and Mitochondrial Sensitivity to Oxidative Stress Determine Induction of Cancer Cell Death by p21

Tekijä Masgras, Ionica, Carrera, Samantha, de Verdier, Petra J., Brennan, Paul, Majid, Aneela, Makhtar, Wan, Tulchinsky, Eugene, Jones, George D. D., Roninson, Igor B., Macip, Salvador
Julkaistu 2012

Effects of conditional depletion of topoisomerase II on cell cycle progression in mammalian cells

Tekijä Gonzalez, Ruth E, Lim, Chang-Uk, Cole, Kelly, Bianchini, Christine Hanko, Schools, Gary P, Davis, Brian E, Wada, Ikuo, Roninson, Igor B, Broude, Eugenia V
Julkaistu 2011

Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types

Tekijä Erokhin, Maksim, Chetverina, Olga, Győrffy, Balázs, Tatarskiy, Victor V., Mogila, Vladic, Shtil, Alexander A., Roninson, Igor B., Moreaux, Jerome, Georgiev, Pavel, Cavalli, Giacomo, Chetverina, Darya
Julkaisussa Cancers (Basel) (2021)

Mediator kinase CDK8/CDK19 drives YAP1-dependent BMP4-induced EMT in cancer

Tekijä Serrao, Anne, Jenkins, Laura M., Chumanevich, Alexander A., Horst, Ben, Liang, Jiaxin, Gatza, Michael L., Lee, Nam Y., Roninson, Igor B., Broude, Eugenia V., Mythreye, Karthikeyan
Julkaisussa Oncogene (2018)