Effects of conditional depletion of topoisomerase II on cell cycle progression in mammalian cells

Topoisomerase II (Topo II) that decatenates newly synthesized DNA is targeted by many anticancer drugs. Some of these drugs stabilize intermediate complexes of DNA with Topo II and others act as catalytic inhibitors of Topo II. Simultaneous depletion of Topo IIα and Topo IIβ, the two isoforms of mam...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Gonzalez, Ruth E, Lim, Chang-Uk, Cole, Kelly, Bianchini, Christine Hanko, Schools, Gary P, Davis, Brian E, Wada, Ikuo, Roninson, Igor B, Broude, Eugenia V
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2011
Assuntos:
Report
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356834/
https://ncbi.nlm.nih.gov/pubmed/22067657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.20.17778
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares