RNAi medicine for the brain: progresses and challenges

ανά Boudreau, Ryan L., Rodríguez-Lebrón, Edgardo, Davidson, Beverly L.
Έκδοση 2011

Unexpected off-targeting effects of anti-huntingtin ribozymes and siRNA in vivo

ανά Denovan-Wright, Eileen M., Rodriguez-Lebron, Edgardo, Lewin, Alfred S., Mandel, Ronald J.
Έκδοση 2007

Splice isoform-specific suppression of the Ca(V)2.1 variant underlying Spinocerebellar ataxia type 6

ανά Tsou, Wei-Ling, Soong, Bing-Wen, Paulson, Henry L., Rodríguez-Lebrón, Edgardo
Έκδοση 2011

Altered Purkinje cell miRNA expression and SCA1 pathogenesis

ανά Rodriguez-Lebron, Edgardo, Liu, Gumei, Keiser, Megan, Belhke, Mark A., Davidson, Beverly L.
Έκδοση 2013

Intrastriatal rAAV-Mediated Delivery of Anti-huntingtin shRNAs Induces Partial Reversal of Disease Progression in R6/1 Huntington’s Disease Transgenic Mice

ανά Rodriguez-Lebron, Edgardo, Denovan-Wright, Eileen M., Nash, Kevin, Lewin, Alfred S., Mandel, Ronald J.
Έκδοση 2005

Allele-specific RNAi Mitigates Phenotypic Progression in a Transgenic Model of Alzheimer's Disease

ανά Rodríguez-Lebrón, Edgardo, Gouvion, Cynthia M, Moore, Steven A, Davidson, Beverly L, Paulson, Henry L
Έκδοση 2009

N-terminal sequences in Matrin 3 mediate phase separation into droplet-like structures that recruit TDP43 variants lacking RNA binding elements

ανά Gallego-Iradi, M. Carolina, Strunk, Haley, Crown, Anthony M., Davila, Rachel, Brown, Hilda, Rodriguez-Lebron, Edgardo, Borchelt, David R.
Τόπος έκδοσης Lab Invest (2019)

Silencing Mutant ATXN3 Expression Resolves Molecular Phenotypes in SCA3 Transgenic Mice

ανά Rodríguez-Lebrón, Edgardo, Costa, Maria doCarmo, Luna-Cancalon, Katiuska, Peron, Therese M, Fischer, Svetlana, Boudreau, Ryan L, Davidson, Beverly L, Paulson, Henry L
Έκδοση 2013

CHIP Suppresses Polyglutamine Aggregation and Toxicity In Vitro and In Vivo

ανά Miller, Victor M., Nelson, Rick F., Gouvion, Cynthia M., Williams, Aislinn, Rodriguez-Lebron, Edgardo, Harper, Scott Q., Davidson, Beverly L., Rebagliati, Michael R., Paulson, Henry L.
Τόπος έκδοσης J Neurosci (2005)

Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP

ανά Scaglione, K. Matthew, Zavodszky, Eszter, Todi, Sokol V., Patury, Srikanth, Xu, Ping, Rodríguez-Lebrón, Edgardo, Fischer, Svetlana, Konen, John, Djarmati, Ana, Peng, Junmin, Gestwicki, Jason E., Paulson, Henry L.
Έκδοση 2011

Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy

ανά Iradi, M. Carolina Gallego, Triplett, Judy C., Thomas, James D., Davila, Rachel, Crown, Anthony M., Brown, Hilda, Lewis, Jada, Swanson, Maurice S., Xu, Guilian, Rodriguez-Lebron, Edgardo, Borchelt, David R.
Τόπος έκδοσης Sci Rep (2018)

Toward RNAi Therapy for the Polyglutamine Disease Machado–Joseph Disease

ανά do Carmo Costa, Maria, Luna-Cancalon, Katiuska, Fischer, Svetlana, Ashraf, Naila S, Ouyang, Michelle, Dharia, Rahil M, Martin-Fishman, Lucas, Yang, Yemen, Shakkottai, Vikram G, Davidson, Beverly L, Rodríguez-Lebrón, Edgardo, Paulson, Henry L
Έκδοση 2013

rAAV-based brain slice culture models of Alzheimer’s and Parkinson’s disease inclusion pathologies

ανά Croft, Cara L., Cruz, Pedro E., Ryu, Daniel H., Ceballos-Diaz, Carolina, Strang, Kevin H., Woody, Brittany M., Lin, Wen-Lang, Deture, Michael, Rodríguez-Lebrón, Edgardo, Dickson, Dennis W., Chakrabarty, Paramita, Levites, Yona, Giasson, Benoit I., Golde, Todd E.
Τόπος έκδοσης J Exp Med (2019)