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Altered Purkinje cell miRNA expression and SCA1 pathogenesis

Spinocerebellar ataxia type 1 (SCA1) is a dominantly inherited neurodegenerative disorder caused by polyglutamine repeat expansions in Ataxin-1. Recent evidence supports a role for microRNA (miRNAs) deregulation in SCA1 pathogenesis. However, the extent to which miRNAs may modulate the onset, progre...

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Detalles Bibliográficos
Main Authors: Rodriguez-Lebron, Edgardo, Liu, Gumei, Keiser, Megan, Belhke, Mark A., Davidson, Beverly L.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3629010/
https://ncbi.nlm.nih.gov/pubmed/23376683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2013.01.019
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