Allele-specific RNAi Mitigates Phenotypic Progression in a Transgenic Model of Alzheimer's Disease

Despite recent advances suggesting new therapeutic targets, Alzheimer's disease (AD) remains incurable. Aberrant production and accumulation of the Aβ peptide resulting from altered processing of the amyloid precursor protein (APP) is central to the pathogenesis of disease, particularly in domi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Rodríguez-Lebrón, Edgardo, Gouvion, Cynthia M, Moore, Steven A, Davidson, Beverly L, Paulson, Henry L
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2009
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835271/
https://ncbi.nlm.nih.gov/pubmed/19532137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.123
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