Allele-specific RNAi Mitigates Phenotypic Progression in a Transgenic Model of Alzheimer's Disease

Despite recent advances suggesting new therapeutic targets, Alzheimer's disease (AD) remains incurable. Aberrant production and accumulation of the Aβ peptide resulting from altered processing of the amyloid precursor protein (APP) is central to the pathogenesis of disease, particularly in domi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rodríguez-Lebrón, Edgardo, Gouvion, Cynthia M, Moore, Steven A, Davidson, Beverly L, Paulson, Henry L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2009
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835271/
https://ncbi.nlm.nih.gov/pubmed/19532137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.123
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