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Validating RNAi Phenotypes in Drosophila Using a Synthetic RNAi-Resistant Transgene

RNA interference (RNAi) is a powerful and widely used approach to investigate gene function, but a major limitation of the approach is the high incidence of non-specific phenotypes that arise due to off-target effects. We previously showed that RNAi-mediated knock-down of pico, which encodes the onl...

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Detalhes bibliográficos
Main Authors: Jonchere, Vincent, Bennett, Daimark
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738578/
https://ncbi.nlm.nih.gov/pubmed/23950943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070489
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