Use of the Surgical Wound Infection Model To Determine the Efficacious Dosing Regimen of Retapamulin, a Novel Topical Antibiotic

Por Rittenhouse, Stephen, Singley, Christine, Hoover, Jennifer, Page, Roni, Payne, David
Publicado em 2006

Stepwise Exposure of Staphylococcus aureus to Pleuromutilins Is Associated with Stepwise Acquisition of Mutations in rplC and Minimally Affects Susceptibility to Retapamulin

Por Gentry, Daniel R., Rittenhouse, Stephen F., McCloskey, Lynn, Holmes, David J.
Publicado em 2007

Reducing Antibacterial Development Risk for GSK1322322 by Exploring Potential Human Dose Regimens in Nonclinical Efficacy Studies Using Immunocompetent Rats

Por Hoover, Jennifer L., Singley, Christine M., Elefante, Philippa, DeMarsh, Peter, Zalacain, Magdalena, Rittenhouse, Stephen
Publicado no Antimicrob Agents Chemother (2017)

A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii

Por Hoover, Jennifer L., Lewandowski, Thomas F., Mininger, Cindy L., Singley, Christine M., Sucoloski, Scott, Rittenhouse, Stephen
Publicado no J Vis Exp (2017)

Efficacy of Cefiderocol against Carbapenem-Resistant Gram-Negative Bacilli in Immunocompetent-Rat Respiratory Tract Infection Models Recreating Human Plasma Pharmacokinetics

Por Matsumoto, Shuhei, Singley, Christine M., Hoover, Jennifer, Nakamura, Rio, Echols, Roger, Rittenhouse, Stephen, Tsuji, Masakatsu, Yamano, Yoshinori
Publicado no Antimicrob Agents Chemother (2017)

Genetic Characterization of Vga ABC Proteins Conferring Reduced Susceptibility to Pleuromutilins in Staphylococcus aureus

Por Gentry, Daniel R., McCloskey, Lynn, Gwynn, Michael N., Rittenhouse, Stephen F., Scangarella, Nicole, Shawar, Ribhi, Holmes, David J.
Publicado em 2008

Pharmacokinetics/Pharmacodynamics of Peptide Deformylase Inhibitor GSK1322322 against Streptococcus pneumoniae, Haemophilus influenzae, and Staphylococcus aureus in Rodent Models o...

Por Hoover, Jennifer, Lewandowski, Thomas, Straub, Robert J., Novick, Steven J., DeMarsh, Peter, Aubart, Kelly, Rittenhouse, Stephen, Zalacain, Magdalena
Publicado no Antimicrob Agents Chemother (2015)

In Vitro Antimicrobial Activity of a Siderophore Cephalosporin, S-649266, against Enterobacteriaceae Clinical Isolates, Including Carbapenem-Resistant Strains

Por Kohira, Naoki, West, Joshua, Ito, Akinobu, Ito-Horiyama, Tsukasa, Nakamura, Rio, Sato, Takafumi, Rittenhouse, Stephen, Tsuji, Masakatsu, Yamano, Yoshinori
Publicado no Antimicrob Agents Chemother (2016)

Selection of Retapamulin, a Novel Pleuromutilin for Topical Use

Por Rittenhouse, Stephen , Biswas, Sanjoy, Broskey, John, McCloskey, Lynn, Moore, Terrance, Vasey, Sandra, West, Joshua, Zalacain, Magdalena, Zonis, Rimma, Payne, David
Publicado em 2006

Variable Sensitivity to Bacterial Methionyl-tRNA Synthetase Inhibitors Reveals Subpopulations of Streptococcus pneumoniae with Two Distinct Methionyl-tRNA Synthetase Genes

Por Gentry, Daniel R., Ingraham, Karen A., Stanhope, Michael J., Rittenhouse, Stephen, Jarvest, Richard L., O'Hanlon, Peter J., Brown, James R., Holmes, David J.
Publicado em 2003

Defining and Combating the Mechanisms of Triclosan Resistance in Clinical Isolates of Staphylococcus aureus

Por Fan, Frank, Yan, Kang, Wallis, Nicola G., Reed, Shannon, Moore, Terrance D., Rittenhouse, Stephen F., DeWolf, Jr., Walter E., Huang, Jianzhong, McDevitt, Damien, Miller, William H., Seefeld, Mark A., Newlander, Kenneth A., Jakas, Dalia R., Head, Martha S., Payne, David J.
Publicado em 2002

Identification of a Series of Tricyclic Natural Products as Potent Broad-Spectrum Inhibitors of Metallo-β-Lactamases

Por Payne, David J., Hueso-Rodríguez, Juan Antonio, Boyd, Helen, Concha, Néstor O., Janson, Cheryl A., Gilpin, Martin, Bateson, John H., Cheever, Christy, Niconovich, Nancy L., Pearson, Stewart, Rittenhouse, Stephen, Tew, David, Díez, Emilio, Pérez, Paloma, de la Fuente, Jesus, Rees, Michael, Rivera-Sagredo, Alfonso
Publicado em 2002

Bacterial Resistance to Leucyl-tRNA Synthetase Inhibitor GSK2251052 Develops during Treatment of Complicated Urinary Tract Infections

Por O'Dwyer, Karen, Spivak, Aaron T., Ingraham, Karen, Min, Sharon, Holmes, David J., Jakielaszek, Charles, Rittenhouse, Stephen, Kwan, Alan L., Livi, George P., Sathe, Ganesh, Thomas, Elizabeth, Van Horn, Stephanie, Miller, Linda A., Twynholm, Monique, Tomayko, John, Dalessandro, Marybeth, Caltabiano, Madelyn, Scangarella-Oman, Nicole E., Brown, James R.
Publicado no Antimicrob Agents Chemother (2014)

Discovery of a Novel and Potent Class of FabI-Directed Antibacterial Agents

Por Payne, David J., Miller, William H., Berry, Valerie, Brosky, John, Burgess, Walter J., Chen, Emile, DeWolf, Jr., Walter E., Fosberry, Andrew P., Greenwood, Rebecca, Head, Martha S., Heerding, Dirk A., Janson, Cheryl A., Jaworski, Deborah D., Keller, Paul M., Manley, Peter J., Moore, Terrance D., Newlander, Kenneth A., Pearson, Stewart, Polizzi, Brian J., Qiu, Xiayang, Rittenhouse, Stephen F., Slater-Radosti, Courtney, Salyers, Kevin L., Seefeld, Mark A., Smyth, Martin G., Takata, Dennis T., Uzinskas, Irene N., Vaidya, Kalindi, Wallis, Nicola G., Winram, Scott B., Yuan, Catherine C. K., Huffman, William F.
Publicado em 2002