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Genetic Characterization of Vga ABC Proteins Conferring Reduced Susceptibility to Pleuromutilins in Staphylococcus aureus

Retapamulin MICs of ≥2 μg/ml were noted for 6 of 5,676 S. aureus recent clinical isolates evaluated. The ABC proteins VgaAv and VgaA were found to be responsible for the reduced susceptibility to pleuromutilins exhibited by these six isolates.

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Autors principals: Gentry, Daniel R., McCloskey, Lynn, Gwynn, Michael N., Rittenhouse, Stephen F., Scangarella, Nicole, Shawar, Ribhi, Holmes, David J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592886/
https://ncbi.nlm.nih.gov/pubmed/18838584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00915-08
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