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Stepwise Exposure of Staphylococcus aureus to Pleuromutilins Is Associated with Stepwise Acquisition of Mutations in rplC and Minimally Affects Susceptibility to Retapamulin

To assess their effects on susceptibility to retapamulin in Staphylococcus aureus, first-, second-, and third-step mutants with elevated MICs to tiamulin and other investigational pleuromutilin compounds were isolated and characterized through exposure to high drug concentrations. All first- and sec...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Gentry, Daniel R., Rittenhouse, Stephen F., McCloskey, Lynn, Holmes, David J.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2007
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891380/
https://ncbi.nlm.nih.gov/pubmed/17404009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01066-06
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