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Unraveling the Metabolic Routes of Retapamulin: Insights into Drug Development of Pleuromutilins
Retapamulin, a semisynthetic pleuromutilin derivative, is exclusively used for the topical short-term medication of impetigo and staphylococcal infections. In the present study, we report that retapamulin is adequately and rapidly metabolized in vitro via various metabolic pathways, such as hydroxyl...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5913982/ https://ncbi.nlm.nih.gov/pubmed/29358298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02388-17 |
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