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Biochemical Characterization of the Interactions of the Novel Pleuromutilin Derivative Retapamulin with Bacterial Ribosomes

Retapamulin is a semisynthetic pleuromutilin derivative being developed as a topical antibiotic for treating bacterial infections of the skin. It is potent in vitro against susceptible and multidrug-resistant organisms commonly associated with bacterial skin infections. We report detailed mode of ac...

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Detalhes bibliográficos
Main Authors: Yan, Kang , Madden, Lenore, Choudhry, Anthony E., Voigt, Christine S., Copeland, Robert A., Gontarek, Richard R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635203/
https://ncbi.nlm.nih.gov/pubmed/16940066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00184-06
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