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Retapamulin Inhibition of Translation and 50S Ribosomal Subunit Formation in Staphylococcus aureus Cells

Retapamulin inhibited protein biosynthesis and cell viability in methicillin-sensitive and methicillin-resistant Staphylococcus aureus organisms. A specific inhibitory effect on 50S ribosomal subunit formation was also found. Pulse-chase labeling experiments confirmed the specific inhibition of 50S...

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Detalhes bibliográficos
Main Authors: Champney, W. Scott, Rodgers, Ward K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043230/
https://ncbi.nlm.nih.gov/pubmed/17562806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00475-07
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