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Solithromycin Inhibition of Protein Synthesis and Ribosome Biogenesis in Staphylococcus aureus, Streptococcus pneumoniae, and Haemophilus influenzae

The continuing increase in antibiotic-resistant microorganisms is driving the search for new antibiotic targets and improved antimicrobial agents. Ketolides are semisynthetic derivatives of macrolide antibiotics, which are effective against certain resistant organisms. Solithromycin (CEM-101) is a n...

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Detalhes bibliográficos
Main Authors: Rodgers, Ward, Frazier, Ashley D., Champney, W. Scott
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623315/
https://ncbi.nlm.nih.gov/pubmed/23318809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02316-12
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