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Use of the Surgical Wound Infection Model To Determine the Efficacious Dosing Regimen of Retapamulin, a Novel Topical Antibiotic

The effect of topically applied retapamulin ointment was evaluated using various dosing regimens in the Staphylococcus aureus and Streptococcus pyogenes wound infection model. Retapamulin (1%, wt/wt) was efficacious using twice-daily (b.i.d.) applications for 4 or 5 days. These data underpinned the...

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Main Authors: Rittenhouse, Stephen, Singley, Christine, Hoover, Jennifer, Page, Roni, Payne, David
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635196/
https://ncbi.nlm.nih.gov/pubmed/17065626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00183-06
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