Determining the Binding Affinity of Therapeutic Monoclonal Antibodies towards Their Native Unpurified Antigens in Human Serum

著者: Bee, Christine, Abdiche, Yasmina N., Pons, Jaume, Rajpal, Arvind
出版事項 2013

A general method for greatly improving the affinity of antibodies by using combinatorial libraries

著者: Rajpal, Arvind, Beyaz, Nurten, Haber, Lauric, Cappuccilli, Guido, Yee, Helena, Bhatt, Ramesh R., Takeuchi, Toshihiko, Lerner, Richard A., Crea, Roberto
出版事項 2005

Exploring the Dynamic Range of the Kinetic Exclusion Assay in Characterizing Antigen-Antibody Interactions

著者: Bee, Christine, Abdiche, Yasmina N., Stone, Donna M., Collier, Sierra, Lindquist, Kevin C., Pinkerton, Alanna C., Pons, Jaume, Rajpal, Arvind
出版事項 2012

High-Throughput Epitope Binning Assays on Label-Free Array-Based Biosensors Can Yield Exquisite Epitope Discrimination That Facilitates the Selection of Monoclonal Antibodies with...

著者: Abdiche, Yasmina Noubia, Miles, Adam, Eckman, Josh, Foletti, Davide, Van Blarcom, Thomas J., Yeung, Yik Andy, Pons, Jaume, Rajpal, Arvind
出版事項 2014

Production of soluble and active microbial transglutaminase in Escherichia coli for site‐specific antibody drug conjugation

著者: Rickert, Mathias, Strop, Pavel, Lui, Victor, Melton‐Witt, Jody, Farias, Santiago Esteban, Foletti, Davide, Shelton, David, Pons, Jaume, Rajpal, Arvind
出版年 Protein Sci (2015)

Transcriptional activation of known and novel apoptotic pathways by Nur77 orphan steroid receptor

著者: Rajpal, Arvind, Cho, Yuri A., Yelent, Biana, Koza-Taylor, Petra H., Li, Dongling, Chen, Elaine, Whang, Michael, Kang, Chulho, Turi, Thomas G., Winoto, Astar
出版事項 2003

Structures of mouse and human GITR–GITRL complexes reveal unique TNF superfamily interactions

著者: Wang, Feng, Chau, Bryant, West, Sean M., Kimberlin, Christopher R., Cao, Fei, Schwarz, Flavio, Aguilar, Barbara, Han, Minhua, Morishige, Winse, Bee, Christine, Dollinger, Gavin, Rajpal, Arvind, Strop, Pavel
出版年 Nat Commun (2021)

The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity

著者: Abdiche, Yasmina Noubia, Yeung, Yik Andy, Chaparro-Riggers, Javier, Barman, Ishita, Strop, Pavel, Chin, Sherman Michael, Pham, Amber, Bolton, Gary, McDonough, Dan, Lindquist, Kevin, Pons, Jaume, Rajpal, Arvind
出版年 MAbs (2015)

RN765C, a low affinity EGFR antibody drug conjugate with potent anti-tumor activity in preclinical solid tumor models

著者: Wong, Oi Kwan, Tran, Thomas-Toan, Ho, Wei-Hsien, Casas, Meritxell Galindo, Au, Melinda, Bateman, Marjorie, Lindquist, Kevin C., Rajpal, Arvind, Shelton, David L., Strop, Pavel, Liu, Shu-Hui
出版年 Oncotarget (2018)

Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire

著者: Glanville, Jacob, Zhai, Wenwu, Berka, Jan, Telman, Dilduz, Huerta, Gabriella, Mehta, Gautam R., Ni, Irene, Mei, Li, Sundar, Purnima D., Day, Giles M. R., Cox, David, Rajpal, Arvind, Pons, Jaume
出版事項 2009

High-Affinity IgG Antibodies Develop Naturally in Ig-Knockout Rats Carrying Germline Human IgH/Igκ/Igλ Loci Bearing the Rat C(H) Region

著者: Osborn, Michael J., Ma, Biao, Avis, Suzanne, Binnie, Ashleigh, Dilley, Jeanette, Yang, Xi, Lindquist, Kevin, Ménoret, Séverine, Iscache, Anne-Laure, Ouisse, Laure-Hélène, Rajpal, Arvind, Anegon, Ignacio, Neuberger, Michael S., Buelow, Roland, Brüggemann, Marianne
出版事項 2013

Correction: High Affinity IgG Antibodies Develop Naturally in Ig-Knockout Rats Carrying Germline Human IgH/Igκ/Igλ Loci Bearing the Rat C(H) Region

著者: Osborn, Michael J., Ma, Biao, Avis, Suzanne, Binnie, Ashleigh, Dilley, Jeanette, Yang, Xi, Lindquist, Kevin, Ménoret, Séverine, Iscache, Anne-Laure, Ouisse, Laure-Hélène, Rajpal, Arvind, Anegon, Ignacio, Neuberger, Michael S., Buelow, Roland, Brüggemann, Marianne
出版年 J Immunol (2013)

Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation

著者: Glanville, Jacob, Kuo, Tracy C., von Büdingen, H.-Christian, Guey, Lin, Berka, Jan, Sundar, Purnima D., Huerta, Gabriella, Mehta, Gautam R., Oksenberg, Jorge R., Hauser, Stephen L., Cox, David R., Rajpal, Arvind, Pons, Jaume
出版事項 2011

Anti–IL-7 receptor-α reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function

著者: Lee, Li-Fen, Logronio, Kathryn, Tu, Guang Huan, Zhai, Wenwu, Ni, Irene, Mei, Li, Dilley, Jeanette, Yu, Jessica, Rajpal, Arvind, Brown, Colleen, Appah, Charles, Chin, Sherman Michael, Han, Bora, Affolter, Timothy, Lin, John C.
出版事項 2012

Modulation of P2X3 and P2X2/3 Receptors by Monoclonal Antibodies

著者: Shcherbatko, Anatoly, Foletti, Davide, Poulsen, Kris, Strop, Pavel, Zhu, Guoyun, Hasa-Moreno, Adela, Melton Witt, Jody, Loo, Carole, Krimm, Stellanie, Pios, Ariel, Yu, Jessica, Brown, Colleen, Lee, John K., Stroud, Robert, Rajpal, Arvind, Shelton, David
出版年 J Biol Chem (2016)

Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain

著者: Shcherbatko, Anatoly, Rossi, Andrea, Foletti, Davide, Zhu, Guoyun, Bogin, Oren, Galindo Casas, Meritxell, Rickert, Mathias, Hasa-Moreno, Adela, Bartsevich, Victor, Crameri, Andreas, Steiner, Alexander R., Henningsen, Robert, Gill, Avinash, Pons, Jaume, Shelton, David L., Rajpal, Arvind, Strop, Pavel
出版年 J Biol Chem (2016)

A method for integrative structure determination of protein-protein complexes

著者: Schneidman-Duhovny, Dina, Rossi, Andrea, Avila-Sakar, Agustin, Kim, Seung Joong, Velázquez-Muriel, Javier, Strop, Pavel, Liang, Hong, Krukenberg, Kristin A., Liao, Maofu, Kim, Ho Min, Sobhanifar, Solmaz, Dötsch, Volker, Rajpal, Arvind, Pons, Jaume, Agard, David A., Cheng, Yifan, Sali, Andrej
出版事項 2012

Germline-encoded neutralization of a Staphylococcus aureus virulence factor by the human antibody repertoire

著者: Yeung, Yik Andy, Foletti, Davide, Deng, Xiaodi, Abdiche, Yasmina, Strop, Pavel, Glanville, Jacob, Pitts, Steven, Lindquist, Kevin, Sundar, Purnima D., Sirota, Marina, Hasa-Moreno, Adela, Pham, Amber, Melton Witt, Jody, Ni, Irene, Pons, Jaume, Shelton, David, Rajpal, Arvind, Chaparro-Riggers, Javier
出版年 Nat Commun (2016)

Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugates

著者: Costa, Maria José, Kudaravalli, Jyothirmayee, Ma, Jing-Tyan, Ho, Wei-Hsien, Delaria, Kathy, Holz, Charles, Stauffer, Angela, Chunyk, Allison Given, Zong, Qing, Blasi, Eileen, Buetow, Bernard, Tran, Thomas-Toan, Lindquist, Kevin, Dorywalska, Magdalena, Rajpal, Arvind, Shelton, David L., Strop, Pavel, Liu, Shu-Hui
出版年 Sci Rep (2019)

Design and characterization of mouse IgG1 and IgG2a bispecific antibodies for use in syngeneic models

著者: Wang, Feng, Tsai, Jordan C., Davis, Jonathan H., Chau, Bryant, Dong, Jia, West, Sean M., Hogan, Jason M., Wheeler, Matthew L., Bee, Christine, Morishige, Winse, Cayton, Thomas, David-brown, Donata, Zhang, Chengyue, Kozhich, Alexander, Sproul, Tim, Dollinger, Gavin, Rajpal, Arvind, Strop, Pavel
出版年 MAbs (2019)