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Production of soluble and active microbial transglutaminase in Escherichia coli for site‐specific antibody drug conjugation

Applications of microbial transglutaminase (mTGase) produced from Streptomyces mobarensis (S. mobarensis) were recently extended from food to pharmaceutical industry. To use mTGase for clinical applications, like generation of site specific antibody drug conjugates, it would be beneficial to manufac...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Rickert, Mathias, Strop, Pavel, Lui, Victor, Melton‐Witt, Jody, Farias, Santiago Esteban, Foletti, Davide, Shelton, David, Pons, Jaume, Rajpal, Arvind
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4815333/
https://ncbi.nlm.nih.gov/pubmed/26481561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2833
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