pH-dependent Binding Engineering Reveals an FcRn Affinity Threshold That Governs IgG Recycling

Por Borrok, M. Jack, Wu, Yanli, Beyaz, Nurten, Yu, Xiang-Qing, Oganesyan, Vaheh, Dall'Acqua, William F., Tsui, Ping
Publicado no J Biol Chem (2015)

A general method for greatly improving the affinity of antibodies by using combinatorial libraries

Por Rajpal, Arvind, Beyaz, Nurten, Haber, Lauric, Cappuccilli, Guido, Yee, Helena, Bhatt, Ramesh R., Takeuchi, Toshihiko, Lerner, Richard A., Crea, Roberto
Publicado em 2005

Enhancement of antibody-dependent cell-mediated cytotoxicity by endowing IgG with FcαRI (CD89) binding

Por Borrok, M Jack, Luheshi, Nadia M, Beyaz, Nurten, Davies, Gareth C, Legg, James W, Wu, Herren, Dall'Acqua, William F, Tsui, Ping
Publicado no MAbs (2015)

Enhancing IgG distribution to lung mucosal tissue improves protective effect of anti–Pseudomonas aeruginosa antibodies

Por Borrok, M. Jack, DiGiandomenico, Antonio, Beyaz, Nurten, Marchetti, Gabriela M., Barnes, Arnita S., Lekstrom, Kristen J., Phipps, Sandrina S., McCarthy, Michael P., Wu, Herren, Dall’Acqua, William F., Tsui, Ping, Gupta, Ruchi
Publicado no JCI Insight (2018)