Transcriptional silencing of γ-globin by BCL11A involves long-range interactions and cooperation with SOX6

por Xu, Jian, Sankaran, Vijay G., Ni, Min, Menne, Tobias F., Puram, Rishi V., Kim, Woojin, Orkin, Stuart H.
Publicado 2010

The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia

por Li, Hubo, Mar, Brenton G., Zhang, Huadi, Puram, Rishi V., Vazquez, Francisca, Weir, Barbara A., Hahn, William C., Ebert, Benjamin, Pellman, David
Publicado en Blood (2017)

Generation of mouse models of myeloid malignancy with combinatorial genetic lesions using CRISPR-Cas9 genome editing

por Heckl, Dirk, Kowalczyk, Monika S., Yudovich, David, Belizaire, Roger, Puram, Rishi V., McConkey, Marie E., Thielke, Anne, Aster, Jon C., Regev, Aviv, Ebert, Benjamin L.
Publicado 2014

Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia

por Järås, Marcus, Miller, Peter G., Chu, Lisa P., Puram, Rishi V., Fink, Emma C., Schneider, Rebekka K., Al-Shahrour, Fatima, Peña, Pablo, Breyfogle, L. Jordan, Hartwell, Kimberly A., McConkey, Marie E., Cowley, Glenn S., Root, David E., Kharas, Michael G., Mullally, Ann, Ebert, Benjamin L.
Publicado 2014

Core circadian clock genes regulate leukemia stem cells in AML

por Puram, Rishi V., Kowalczyk, Monika S., de Boer, Carl G., Schneider, Rebekka K., Miller, Peter G., McConkey, Marie, Tothova, Zuzana, Tejero, Héctor, Heckl, Dirk, Järås, Marcus, Chen, Michelle C., Li, Hubo, Tamayo, Alfred, Cowley, Glenn S., Rozenblatt-Rosen, Orit, Al-Shahrour, Fatima, Regev, Aviv, Ebert, Benjamin L.
Publicado en Cell (2016)

In Vivo RNA Interference Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling

por Miller, Peter G., Al-Shahrour, Fatima, Hartwell, Kimberly A., Chu, Lisa P., Järås, Marcus, Puram, Rishi V., Puissant, Alexandre, Callahan, Kevin P., Ashton, John, McConkey, Marie E., Poveromo, Luke P., Cowley, Glenn S., Kharas, Michael G., Labelle, Myriam, Shterental, Sebastian, Fujisaki, Joji, Silberstein, Lev, Alexe, Gabriela, Al-Hajj, Muhammad A., Shelton, Christopher A., Armstrong, Scott A., Root, David E., Scadden, David T., Hynes, Richard O., Mukherjee, Siddhartha, Stegmaier, Kimberly, Jordan, Craig T., Ebert, Benjamin L.
Publicado 2013