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The EMT regulator ZEB2 is a novel dependency of human and murine acute myeloid leukemia
Acute myeloid leukemia (AML) is a heterogeneous disease with complex molecular pathophysiology. To systematically characterize AML’s genetic dependencies, we conducted genome-scale short hairpin RNA screens in 17 AML cell lines and analyzed dependencies relative to parallel screens in 199 cell lines...
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| Publicado no: | Blood |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5270388/ https://ncbi.nlm.nih.gov/pubmed/27756750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-05-714493 |
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