Axonal degeneration in an Alzheimer mouse model is PS1 gene dose dependent and linked to intraneuronal Aβ accumulation

di Christensen, Ditte Z., Huettenrauch, Melanie, Mitkovski, Miso, Pradier, Laurent, Wirths, Oliver
Pubblicazione 2014

Neural Differentiation of Embryonic Stem Cells In Vitro: A Road Map to Neurogenesis in the Embryo

di Abranches, Elsa, Silva, Margarida, Pradier, Laurent, Schulz, Herbert, Hummel, Oliver, Henrique, Domingos, Bekman, Evguenia
Pubblicazione 2009

FE65 in Alzheimer’s Disease : Neuronal Distribution and Association with Neurofibrillary Tangles

di Delatour, Benoît, Mercken, Luc, El Hachimi, Khalid H., Colle, Marie-Anne, Pradier, Laurent, Duyckaerts, Charles
Pubblicazione 2001

Subcellular Topography of Neuronal Aβ Peptide in APPxPS1 Transgenic Mice

di Langui, Dominique, Girardot, Nadège, Hamid El Hachimi, Khalid, Allinquant, Bernadette, Blanchard, Véronique, Pradier, Laurent, Duyckaerts, Charles
Pubblicazione 2004

Neuroprotective role of PKR in a model of neurodegeneration due to mild impairment of oxidative metabolism

di Mouton-Liger, François, Rebillat, Anne-Sophie, Gourmaud, Sarah, Leguen, Audrey, Paquet, Claire, Pradier, Laurent, Rooney, Thomas, Hugon, Jacques
Pubblicazione 2013

The PKR Activator PACT Is Induced by Aβ: Involvement in Alzheimer's Disease

di Paquet, Claire, Mouton‐Liger, François, Meurs, Eliane F., Mazot, Pierre, Bouras, Constantin, Pradier, Laurent, Gray, Françoise, Hugon, Jacques
Pubblicato in Brain Pathol (2011)

Reporter cell assay for human CD33 validated by specific antibodies and human iPSC-derived microglia

di Wißfeld, Jannis, Mathews, Mona, Mossad, Omar, Picardi, Paola, Cinti, Alessandro, Redaelli, Loredana, Pradier, Laurent, Brüstle, Oliver, Neumann, Harald
Pubblicato in Sci Rep (2021)

Intraneuronal APP/Aβ Trafficking and Plaque Formation in β‐Amyloid Precursor Protein and Presenilin‐1 Transgenic Mice

di Wirths, Oliver, Multhaup, Gerd, Czech, Christian, Feldmann, Nicole, Blanchard, Véronique, Tremp, Günter, Beyreuther, Konrad, Pradier, Laurent, Bayer, Thomas A.
Pubblicato in Brain Pathol (2006)

In Vivo Detection of Amyloid Plaques by Gadolinium-Stained MRI Can Be Used to Demonstrate the Efficacy of an Anti-amyloid Immunotherapy

di Santin, Mathieu D., Vandenberghe, Michel E., Herard, Anne-Sophie, Pradier, Laurent, Cohen, Caroline, Debeir, Thomas, Delzescaux, Thierry, Rooney, Thomas, Dhenain, Marc
Pubblicato in Front Aging Neurosci (2016)

LRP1 Has a Predominant Role in Production over Clearance of Aβ in a Mouse Model of Alzheimer’s Disease

di Van Gool, Bart, Storck, Steffen E., Reekmans, Sara M., Lechat, Benoit, Gordts, Philip L. S. M., Pradier, Laurent, Pietrzik, Claus U., Roebroek, Anton J. M.
Pubblicato in Mol Neurobiol (2019)

TC‐1734: An Orally Active Neuronal Nicotinic Acetylcholine Receptor Modulator with Antidepressant, Neuroprotective and Long‐Lasting Cognitive Effects

di Gatto, Gregory J., Bohme, G Andrees, Caldwell, William S., Letchworth, Sharon R., Traina, Vincent M., Obinu, M. Carmen, Laville, Michel, Reibaud, Michel, Pradier, Laurent, Dunbar, Geoffrey, Bencherif, Merouane
Pubblicato in CNS Drug Rev (2006)

SAR110894, a potent histamine H3-receptor antagonist, displays disease-modifying activity in a transgenic mouse model of tauopathy

di Delay-Goyet, Philippe, Blanchard, Véronique, Schussler, Nathalie, Lopez-Grancha, Mati, Ménager, Jean, Mary, Véronique, Sultan, Eric, Buzy, Armelle, Guillemot, Jean-Claude, Stemmelin, Jeanne, Bertrand, Philippe, Rooney, Thomas, Pradier, Laurent, Barnéoud, Pascal
Pubblicato in Alzheimers Dement (N Y) (2016)

Hippocampal Neuron Loss Exceeds Amyloid Plaque Load in a Transgenic Mouse Model of Alzheimer’s Disease

di Schmitz, Christoph, Rutten, Bart P. F., Pielen, Andrea, Schäfer, Stephanie, Wirths, Oliver, Tremp, Günter, Czech, Christian, Blanchard, Veronique, Multhaup, Gerd, Rezaie, Payam, Korr, Hubert, Steinbusch, Harry W. M., Pradier, Laurent, Bayer, Thomas A.
Pubblicazione 2004

Gene delivery of a modified antibody to Aβ reduces progression of murine Alzheimer’s disease

di Elmer, Bradford M., Swanson, Kurt A., Bangari, Dinesh S., Piepenhagen, Peter A., Roberts, Errin, Taksir, Tatyana, Guo, Lei, Obinu, Maria-Carmen, Barneoud, Pascal, Ryan, Susan, Zhang, Bailin, Pradier, Laurent, Yang, Zhi-Yong, Nabel, Gary J.
Pubblicato in PLoS One (2019)

High-throughput 3D whole-brain quantitative histopathology in rodents

di Vandenberghe, Michel E., Hérard, Anne-Sophie, Souedet, Nicolas, Sadouni, Elmahdi, Santin, Mathieu D., Briet, Dominique, Carré, Denis, Schulz, Jocelyne, Hantraye, Philippe, Chabrier, Pierre-Etienne, Rooney, Thomas, Debeir, Thomas, Blanchard, Véronique, Pradier, Laurent, Dhenain, Marc, Delzescaux, Thierry
Pubblicato in Sci Rep (2016)

Massive CA1/2 Neuronal Loss with Intraneuronal and N-Terminal Truncated Aβ(42) Accumulation in a Novel Alzheimer Transgenic Model

di Casas, Caty, Sergeant, Nicolas, Itier, Jean-Michel, Blanchard, Véronique, Wirths, Oliver, van der Kolk, Nicolien, Vingtdeux, Valérie, van de Steeg, Evita, Ret, Gwenaëlle, Canton, Thierry, Drobecq, Hervé, Clark, Allan, Bonici, Bruno, Delacourte, André, Benavides, Jesús, Schmitz, Christoph, Tremp, Günter, Bayer, Thomas A., Benoit, Patrick, Pradier, Laurent
Pubblicazione 2004

SAR228810: an antibody for protofibrillar amyloid β peptide designed to reduce the risk of amyloid-related imaging abnormalities (ARIA)

di Pradier, Laurent, Blanchard-Brégeon, Véronique, Bohme, Andrees, Debeir, Thomas, Menager, Jean, Benoit, Patrick, Barneoud, Pascal, Taupin, Véronique, Bertrand, Philippe, Dugay, Philippe, Cameron, Béatrice, Shi, Yi, Naimi, Souad, Duchesne, Marc, Gagnaire, Marie, Weeden, Tim, Travaline, Tara, Reczek, David, Khiroug, Leonard, Slaoui, Mohamed, Brunel, Pascale, Fukuyama, Hidehiro, Ravetch, Jeffrey, Canton, Thierry, Cohen, Caroline
Pubblicato in Alzheimers Res Ther (2018)

BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr(348) phosphorylation

di Sartori, Maxime, Mendes, Tiago, Desai, Shruti, Lasorsa, Alessia, Herledan, Adrien, Malmanche, Nicolas, Mäkinen, Petra, Marttinen, Mikael, Malki, Idir, Chapuis, Julien, Flaig, Amandine, Vreulx, Anaïs-Camille, Ciancia, Marion, Amouyel, Philippe, Leroux, Florence, Déprez, Benoit, Cantrelle, François-Xavier, Maréchal, Damien, Pradier, Laurent, Hiltunen, Mikko, Landrieu, Isabelle, Kilinc, Devrim, Herault, Yann, Laporte, Jocelyn, Lambert, Jean-Charles
Pubblicato in Acta Neuropathol (2019)

Tetravalent Bispecific Tandem Antibodies Improve Brain Exposure and Efficacy in an Amyloid Transgenic Mouse Model

di Do, Tuan-Minh, Capdevila, Cécile, Pradier, Laurent, Blanchard, Véronique, Lopez-Grancha, Mati, Schussler, Nathalie, Steinmetz, Anke, Beninga, Jochen, Boulay, Denis, Dugay, Philippe, Verdier, Patrick, Aubin, Nadine, Dargazanli, Gihad, Chaves, Catarina, Genet, Elisabeth, Lossouarn, Yves, Loux, Christophe, Michoux, François, Moindrot, Nicolas, Chanut, Franck, Gury, Thierry, Eyquem, Stéphanie, Valente, Delphine, Bergis, Olivier, Rao, Ercole, Lesuisse, Dominique
Pubblicato in Mol Ther Methods Clin Dev (2020)

The FunGenES Database: A Genomics Resource for Mouse Embryonic Stem Cell Differentiation

di Schulz, Herbert, Kolde, Raivo, Adler, Priit, Aksoy, Irène, Anastassiadis, Konstantinos, Bader, Michael, Billon, Nathalie, Boeuf, Hélène, Bourillot, Pierre-Yves, Buchholz, Frank, Dani, Christian, Doss, Michael Xavier, Forrester, Lesley, Gitton, Murielle, Henrique, Domingos, Hescheler, Jürgen, Himmelbauer, Heinz, Hübner, Norbert, Karantzali, Efthimia, Kretsovali, Androniki, Lubitz, Sandra, Pradier, Laurent, Rai, Meena, Reimand, Jüri, Rolletschek, Alexandra, Sachinidis, Agapios, Savatier, Pierre, Stewart, Francis, Storm, Mike P., Trouillas, Marina, Vilo, Jaak, Welham, Melanie J., Winkler, Johannes, Wobus, Anna M., Hatzopoulos, Antonis K.
Pubblicazione 2009