Altered neurogenesis in mouse models of Alzheimer disease

par Wirths, Oliver
Publié dans Neurogenesis (Austin) (2017)

Neuron Loss in Alzheimer’s Disease: Translation in Transgenic Mouse Models

par Wirths, Oliver, Zampar, Silvia
Publié dans Int J Mol Sci (2020)

Chronic Memantine Treatment Ameliorates Behavioral Deficits, Neuron Loss, and Impaired Neurogenesis in a Model of Alzheimer’s Disease

par Stazi, Martina, Wirths, Oliver
Publié dans Mol Neurobiol (2020)

Characterization of a Mouse Model of Alzheimer’s Disease Expressing Aβ4-42 and Human Mutant Tau

par Zampar, Silvia, Wirths, Oliver
Publié dans Int J Mol Sci (2021)

Intracellular Accumulation of Amyloid-Beta – A Predictor for Synaptic Dysfunction and Neuron Loss in Alzheimer's Disease

par Bayer, Thomas A., Wirths, Oliver
Publié 2010

Neuron Loss in Transgenic Mouse Models of Alzheimer's Disease

par Wirths, Oliver, Bayer, Thomas A.
Publié 2010

Focusing the amyloid cascade hypothesis on N-truncated Abeta peptides as drug targets against Alzheimer’s disease

par Bayer, Thomas A., Wirths, Oliver
Publié 2014

Loss of Hippocampal Calretinin and Parvalbumin Interneurons in the 5XFAD Mouse Model of Alzheimer’s Disease

par Giesers, Naomi K., Wirths, Oliver
Publié dans ASN Neuro (2020)

Effects of Long-Term Environmental Enrichment on Anxiety, Memory, Hippocampal Plasticity and Overall Brain Gene Expression in C57BL6 Mice

par Hüttenrauch, Melanie, Salinas, Gabriela, Wirths, Oliver
Publié dans Front Mol Neurosci (2016)

Pyroglutamate Amyloid-β (Aβ): A Hatchet Man in Alzheimer Disease

par Jawhar, Sadim, Wirths, Oliver, Bayer, Thomas A.
Publié 2011

Axonal degeneration in an Alzheimer mouse model is PS1 gene dose dependent and linked to intraneuronal Aβ accumulation

par Christensen, Ditte Z., Huettenrauch, Melanie, Mitkovski, Miso, Pradier, Laurent, Wirths, Oliver
Publié 2014

The Cannabinoid CB1/CB2 Agonist WIN55212.2 Promotes Oligodendrocyte Differentiation In Vitro and Neuroprotection During the Cuprizone‐Induced Central Nervous System Demyelination

par Tomas‐Roig, Jordi, Wirths, Oliver, Salinas‐Riester, Gabriela, Havemann‐Reinecke, Ursula
Publié dans CNS Neurosci Ther (2016)

Physical Activity Ameliorates Impaired Hippocampal Neurogenesis in the Tg4-42 Mouse Model of Alzheimer’s Disease

par Gerberding, Anna-Lina, Zampar, Silvia, Stazi, Martina, Liebetanz, David, Wirths, Oliver
Publié dans ASN Neuro (2019)

Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model

par Wirths, Oliver, Breyhan, Henning, Cynis, Holger, Schilling, Stephan, Demuth, Hans-Ulrich, Bayer, Thomas A.
Publié 2009

Accumulation of intraneuronal Aβ correlates with ApoE4 genotype

par Christensen, Ditte Z., Schneider-Axmann, Thomas, Lucassen, Paul J., Bayer, Thomas A., Wirths, Oliver
Publié 2010

Overexpression of Glutaminyl Cyclase, the Enzyme Responsible for Pyroglutamate Aβ Formation, Induces Behavioral Deficits, and Glutaminyl Cyclase Knock-out Rescues the Behavioral Ph...

par Jawhar, Sadim, Wirths, Oliver, Schilling, Stephan, Graubner, Sigrid, Demuth, Hans-Ulrich, Bayer, Thomas A.
Publié 2011

Circulating immune complexes of Aβ and IgM in plasma of patients with Alzheimer’s disease

par Marcello, Andrea, Wirths, Oliver, Schneider-Axmann, Thomas, Degerman-Gunnarsson, Malin, Lannfelt, Lars, Bayer, Thomas A.
Publié 2009

Abundant pyroglutamate-modified ABri and ADan peptides in extracellular and vascular amyloid deposits in familial British and Danish dementias

par Saul, Anika, Lashley, Tammaryn, Revesz, Tamas, Holton, Janice, Ghiso, Jorge A., Coomaraswamy, Janaky, Wirths, Oliver
Publié 2012

Key Factors in Alzheimer's Disease: β‐amyloid Precursor Protein Processing, Metabolism and Intraneuronal Transport

par Bayer, Thomas A., Wirths, Oliver, Majtényi, Katalin, Hartmann, Tobias, Multhaup, Gerd, Beyreuther, Konrad, Czech, Christian
Publié dans Brain Pathol (2006)

Glycoprotein NMB: a novel Alzheimer’s disease associated marker expressed in a subset of activated microglia

par Hüttenrauch, Melanie, Ogorek, Isabella, Klafki, Hans, Otto, Markus, Stadelmann, Christine, Weggen, Sascha, Wiltfang, Jens, Wirths, Oliver
Publié dans Acta Neuropathol Commun (2018)