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Intracellular Accumulation of Amyloid-Beta – A Predictor for Synaptic Dysfunction and Neuron Loss in Alzheimer's Disease

Despite of long-standing evidence that beta-amyloid (Aβ) peptides have detrimental effects on synaptic function, the relationship between Aβ, synaptic and neuron loss is largely unclear. During the last years there is growing evidence that early intraneuronal accumulation of Aβ peptides is one of th...

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Sonraí Bibleagrafaíochta
Main Authors: Bayer, Thomas A., Wirths, Oliver
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Research Foundation 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879032/
https://ncbi.nlm.nih.gov/pubmed/20552046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2010.00008
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