Amyloid Beta Oligomers Target to Extracellular and Intracellular Neuronal Synaptic Proteins in Alzheimer's Disease

Introduction: β-Amyloid protein (Aβ) putatively plays a seminal role in synaptic loss in Alzheimer's disease (AD). While there is no consensus regarding the synaptic-relevant species of Aβ, it is known that Aβ oligomers (AβOs) are noticeably increased in the early stages of AD, localizing at or...

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Detalhes bibliográficos
Publicado no:Front Neurol
Main Authors: Ding, Yu, Zhao, Jiahui, Zhang, Xunle, Wang, Shanshan, Viola, Kirsten L., Chow, Frances E., Zhang, Yang, Lippa, Carol, Klein, William L., Gong, Yuesong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neurology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6838211/
https://ncbi.nlm.nih.gov/pubmed/31736856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2019.01140
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