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Amyloid-β oligomers are sequestered by both intracellular and extracellular chaperones

The aberrant aggregation of the amyloid-β peptide into β-sheet rich, fibrillar structures proceeds via a heterogeneous ensemble of oligomeric intermediates that have been associated with neurotoxicity in Alzheimer’s disease (AD). Of particular interest in this context are the mechanisms by which mol...

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Detaylı Bibliyografya
Yayımlandı:Biochemistry
Asıl Yazarlar: Narayan, Priyanka, Meehan, Sarah, Carver, John A., Wilson, Mark R., Dobson, Christopher M., Klenerman, David
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981287/
https://ncbi.nlm.nih.gov/pubmed/23106396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301277k
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