Single Molecule Characterization of the Interactions between Amyloid-β Peptides and the Membranes of Hippocampal Cells

[Image: see text] Oligomers of the 40 and 42 residue amyloid-β peptides (Aβ40 and Aβ42) have been implicated in the neuronal damage and impaired cognitive function associated with Alzheimer’s disease. However, little is known about the specific mechanisms by which these misfolded species induce such...

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Detalhes bibliográficos
Main Authors: Narayan, Priyanka, Ganzinger, Kristina A., McColl, James, Weimann, Laura, Meehan, Sarah, Qamar, Seema, Carver, John A., Wilson, Mark R., St. George-Hyslop, Peter, Dobson, Christopher M., Klenerman, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561772/
https://ncbi.nlm.nih.gov/pubmed/23339742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3103567
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