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Pyroglutamate Amyloid-β (Aβ): A Hatchet Man in Alzheimer Disease
Pyroglutamate-modified amyloid-β (Aβ(pE3)) peptides are gaining considerable attention as potential key participants in the pathology of Alzheimer disease (AD) due to their abundance in AD brain, high aggregation propensity, stability, and cellular toxicity. Transgenic mice that produce high levels...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3234707/ https://ncbi.nlm.nih.gov/pubmed/21965666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R111.288308 |
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