Differential transcript usage unravels gene expression alterations in Alzheimer’s disease human brains

od Marques-Coelho, Diego, Iohan, Lukas da Cruz Carvalho, Melo de Farias, Ana Raquel, Flaig, Amandine, Lambert, Jean-Charles, Costa, Marcos Romualdo
Izdano u NPJ Aging Mech Dis (2021)

Pyk2 overexpression in postsynaptic neurons blocks amyloid β(1–42)-induced synaptotoxicity in microfluidic co-cultures

od Kilinc, Devrim, Vreulx, Anaïs-Camille, Mendes, Tiago, Flaig, Amandine, Marques-Coelho, Diego, Verschoore, Maxime, Demiautte, Florie, Amouyel, Philippe, Eysert, Fanny, Dourlen, Pierre, Chapuis, Julien, Costa, Marcos R, Malmanche, Nicolas, Checler, Frédéric, Lambert, Jean-Charles
Izdano u Brain Commun (2020)

Tau phosphorylation regulates the interaction between BIN1’s SH3 domain and Tau’s proline-rich domain

od Sottejeau, Yoann, Bretteville, Alexis, Cantrelle, François-Xavier, Malmanche, Nicolas, Demiaute, Florie, Mendes, Tiago, Delay, Charlotte, Alves Dos Alves, Harmony, Flaig, Amandine, Davies, Peter, Dourlen, Pierre, Dermaut, Bart, Laporte, Jocelyn, Amouyel, Philippe, Lippens, Guy, Chapuis, Julien, Landrieu, Isabelle, Lambert, Jean-Charles
Izdano u Acta Neuropathol Commun (2015)

BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr(348) phosphorylation

od Sartori, Maxime, Mendes, Tiago, Desai, Shruti, Lasorsa, Alessia, Herledan, Adrien, Malmanche, Nicolas, Mäkinen, Petra, Marttinen, Mikael, Malki, Idir, Chapuis, Julien, Flaig, Amandine, Vreulx, Anaïs-Camille, Ciancia, Marion, Amouyel, Philippe, Leroux, Florence, Déprez, Benoit, Cantrelle, François-Xavier, Maréchal, Damien, Pradier, Laurent, Hiltunen, Mikko, Landrieu, Isabelle, Kilinc, Devrim, Herault, Yann, Laporte, Jocelyn, Lambert, Jean-Charles
Izdano u Acta Neuropathol (2019)

ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease

od Letronne, Florent, Laumet, Geoffroy, Ayral, Anne-Marie, Chapuis, Julien, Demiautte, Florie, Laga, Mathias, Vandenberghe, Michel E., Malmanche, Nicolas, Leroux, Florence, Eysert, Fanny, Sottejeau, Yoann, Chami, Linda, Flaig, Amandine, Bauer, Charlotte, Dourlen, Pierre, Lesaffre, Marie, Delay, Charlotte, Huot, Ludovic, Dumont, Julie, Werkmeister, Elisabeth, Lafont, Franck, Mendes, Tiago, Hansmannel, Franck, Dermaut, Bart, Deprez, Benoit, Hérard, Anne-Sophie, Dhenain, Marc, Souedet, Nicolas, Pasquier, Florence, Tulasne, David, Berr, Claudine, Hauw, Jean-Jacques, Lemoine, Yves, Amouyel, Philippe, Mann, David, Déprez, Rebecca, Checler, Frédéric, Hot, David, Delzescaux, Thierry, Gevaert, Kris, Lambert, Jean-Charles
Izdano u EBioMedicine (2016)

Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism

od Chapuis, Julien, Flaig, Amandine, Grenier-Boley, Benjamin, Eysert, Fanny, Pottiez, Virginie, Deloison, Gaspard, Vandeputte, Alexandre, Ayral, Anne-Marie, Mendes, Tiago, Desai, Shruti, Goate, Alison M., Kauwe, John S. K., Leroux, Florence, Herledan, Adrien, Demiautte, Florie, Bauer, Charlotte, Checler, Fréderic, Petersen, Ronald C., Blennow, Kaj, Zetterberg, Henrik, Minthon, Lennart, Van Deerlin, Vivianna M., Lee, Virginia Man-Yee, Shaw, Leslie M., Trojanowski, John Q., Albert, Marilyn, Moghekar, Abhay, O’Brien, Richard, Peskind, Elaine R., Malmanche, Nicolas, Schellenberg, Gerard D., Dourlen, Pierre, Song, Ok-Ryul, Cruchaga, Carlos, Amouyel, Philippe, Deprez, Benoit, Brodin, Priscille, Lambert, Jean-Charles
Izdano u Acta Neuropathol (2016)