Pyk2 overexpression in postsynaptic neurons blocks amyloid β(1–42)-induced synaptotoxicity in microfluidic co-cultures

Recent meta-analyses of genome-wide association studies identified a number of genetic risk factors of Alzheimer’s disease; however, little is known about the mechanisms by which they contribute to the pathological process. As synapse loss is observed at the earliest stage of Alzheimer’s disease, de...

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Опубликовано в: :Brain Commun
Главные авторы: Kilinc, Devrim, Vreulx, Anaïs-Camille, Mendes, Tiago, Flaig, Amandine, Marques-Coelho, Diego, Verschoore, Maxime, Demiautte, Florie, Amouyel, Philippe, Eysert, Fanny, Dourlen, Pierre, Chapuis, Julien, Costa, Marcos R, Malmanche, Nicolas, Checler, Frédéric, Lambert, Jean-Charles
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2020
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7941669/
https://ncbi.nlm.nih.gov/pubmed/33718872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/braincomms/fcaa139
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