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The new genetic landscape of Alzheimer’s disease: from amyloid cascade to genetically driven synaptic failure hypothesis?

A strong genetic predisposition (60–80% of attributable risk) is present in Alzheimer’s disease (AD). In view of this major genetic component, identification of the genetic risk factors has been a major objective in the AD field with the ultimate aim to better understand the pathological processes....

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Dades bibliogràfiques
Publicat a:Acta Neuropathol
Autors principals: Dourlen, Pierre, Kilinc, Devrim, Malmanche, Nicolas, Chapuis, Julien, Lambert, Jean-Charles
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6660578/
https://ncbi.nlm.nih.gov/pubmed/30982098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-02004-0
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