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Postsynaptic Clustering and Activation of Pyk2 by PSD-95
The tyrosine kinase Pyk2 plays a unique role in intracellular signal transduction by linking Ca(2+) influx to tyrosine phosphorylation, but the molecular mechanism of Pyk2 activation is unknown. We report that Pyk2 oligomerization by antibodies in vitro or overexpression of PSD-95 in PC6-3 cells ind...
Tallennettuna:
| Päätekijät: | , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Society for Neuroscience
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822408/ https://ncbi.nlm.nih.gov/pubmed/20071509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4992-08.2010 |
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