α-Actinin Anchors PSD-95 at Postsynaptic Sites

Despite the central role PSD-95 plays in anchoring postsynaptic AMPARs, how PSD-95 itself is tethered to postsynaptic sites is not well understood. Here we show that the F-actin binding protein α-actinin binds to the very N-terminus of PSD-95. Knock-down (kd) of α-actinin phenocopies kd of PSD-95. M...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Neuron
Main Authors: Matt, Lucas, Kim, Karam, Hergarden, Anne E., Patriarchi, Tommaso, Malik, Zulfiqar A., Park, Deborah K., Chowdhury, Dhrubajyoti, Buonarati, Olivia R., Henderson, Peter B., Saraç, Çiğdem Gökçek, Zhang, Yonghong, Mohapatra, Durga, Horne, Mary C., Ames, James B., Hell, Johannes W.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963734/
https://ncbi.nlm.nih.gov/pubmed/29429936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2018.01.036
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker