Ca(2+)/calmodulin binding to PSD‐95 mediates homeostatic synaptic scaling down

Postsynaptic density protein‐95 (PSD‐95) localizes AMPA‐type glutamate receptors (AMPARs) to postsynaptic sites of glutamatergic synapses. Its postsynaptic displacement is necessary for loss of AMPARs during homeostatic scaling down of synapses. Here, we demonstrate that upon Ca(2+) influx, Ca(2+)/c...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Chowdhury, Dhrubajyoti, Turner, Matthew, Patriarchi, Tommaso, Hergarden, Anne C, Anderson, David, Zhang, Yonghong, Sun, Junqing, Chen, Chao‐Yin, Ames, James B, Hell, Johannes W
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753037/
https://ncbi.nlm.nih.gov/pubmed/29118000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695829
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