Ca(2+)/calmodulin binding to PSD‐95 mediates homeostatic synaptic scaling down

Postsynaptic density protein‐95 (PSD‐95) localizes AMPA‐type glutamate receptors (AMPARs) to postsynaptic sites of glutamatergic synapses. Its postsynaptic displacement is necessary for loss of AMPARs during homeostatic scaling down of synapses. Here, we demonstrate that upon Ca(2+) influx, Ca(2+)/c...

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Vydáno v:EMBO J
Hlavní autoři: Chowdhury, Dhrubajyoti, Turner, Matthew, Patriarchi, Tommaso, Hergarden, Anne C, Anderson, David, Zhang, Yonghong, Sun, Junqing, Chen, Chao‐Yin, Ames, James B, Hell, Johannes W
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5753037/
https://ncbi.nlm.nih.gov/pubmed/29118000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201695829
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