PSD-95 Is Required to Sustain the Molecular Organization of the Postsynaptic Density

PSD-95, a membrane-associated guanylate kinase, is the major scaffolding protein in the excitatory postsynaptic density (PSD) and a potent regulator of synaptic strength. Here we show that PSD-95 is in an extended configuration and positioned into regular arrays of vertical filaments that contact bo...

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Detalhes bibliográficos
Main Authors: Chen, Xiaobing, Nelson, Christopher D., Li, Xiang, Winters, Christine A., Azzam, Rita, Sousa, Alioscka A., Leapman, Richard D., Gainer, Harold, Sheng, Morgan, Reese, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099547/
https://ncbi.nlm.nih.gov/pubmed/21525273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5968-10.2011
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